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RISS 인기검색어
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- 저자 : 이승헌(Seoung Hun Lee) (검색결과 1 건)
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이승헌(Seoung Hun Lee),윤형규(Hyung Gue Yoon),송윤상(Yoon Sang Song),최문영(Moon Young Choi),김석은(Seok Eun Kim),박인석(In Seok Park),장윤식(Yoon Sik Chang),방병기(Byung Kee Bang) 대한내과학회 1994 대한내과학회지 Vol.46 No.1
N/A Background: The Captopril test (Muller, 1986) appears to represent a simple and useful screening tool in the diagnosis of renovascular hypertension. The limitations of the sennsitivity, specificity have been reported under certain circumstances. We performed this study to evaluate the sensitivity, specificity and predictive value of the Captopril test in the diagnosis of renovascular hypertension. Methods: We calculated the sensitivity, specicity and predictive value of the Captopril test in 26patients with clinical suspicion of renovasculr hypertension. We performed the Captopril test and renal angiography in these patients. Results; 1) The Captopril test was positive in 8 patients (30.7%), in whom 26renovascular hypertension were suspected. 2) The mean value of basal and stimulated plasma renin activity were 4.55±1.74ng/ml/hr and 19.89±7.19ng/ml/hr respectively, in 8patients with positive Captopril test. The mean value of percent increase of stimulated PRA was 384±227.9% in these patients. 3) The mean value of basal and stimulated plasma renin activity were 7.27±5.29ng/hr and 8. 78±5.89ng/ ml/hr respectively, in patients with negative Captopril test. The mean value of percent increase of stimulated PRA was 34.61±30.56% in these patients. 4) In patients with postivie Captopril test, there were 4true positive (50%) and 4false positive (50%) by renal angiography. In 18patients with negative Captopril test, there was 1false negative who had abnormal angiography. 5) The sensitivity, specificity and predictive value of the Captopril test were 80%, 81% and 50% respectively. Conclusion: The Captopril test seems to have limitations of sensitivity, specificity and predictive value in the diagnosis of renovascular hypertension. The careful clinical clinical application of Captopril test and renal angiography should be considered in the diagnosis of renovascular hypertension.
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