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한국인가임부에 있어서의 Ortho Novum 2mg ( Norethindrone 2mg with mestranol 0.1mg ) 정의 임상실험 ( 제 1 보 )
윤영선(YS Yoon),이동림(TN Lee) 대한산부인과학회 1966 Obstetrics & Gynecology Science Vol.9 No.2
The Purpose of this study was to know about the effectiveness as well as side effects of this drug as a contraceptive in Korean women. Since August 1965, the study has encom passed a total of 1,205 cycles experienced by 796 patients. The range of use was from one to five cycles. Protection against conception afforded by the medication proved complete insofar as not a single pregnancys occured in any patient while the drug was being taken. Secondary the rapeutic benefits were noted in relief of preexisting menorrhagia and dysmenorrhea in cases. No significant side effects attributable to the use of the durg were noted. Less tthan 1% (7 cases discontinued to have the use of this medication of 2nd cycle. 6 out of 7 cases were caused by nausea, vomitting and gastric disorders. This drug was highly effective as a oralcontraceptive and proved to be devoid of any serious side effects in Korean women.