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경기북부 지역의 Richettsia 질환에 관한 임상적 고찰
전성주(Seoung Ju Chun),이기영(Kee Yeoung Lee),최두혁(Du Hyok Choi),양현억(Hyun Eog Yang) 대한내과학회 1989 대한내과학회지 Vol.36 No.4
N/A Rickettsiosis is one of the most prevailng acute febrile diseases in the northern part of Kyoung Ki Do during harvest-time. We experienced 36 cases of rickettsiosis in this area during 1978. Herein we report the epidemiological and clinical observations with laboratory findings. 1) The disease was prevalent in adult female farmers and the epidemic seasons were fall and early winter. 2) The serologic test revealed a positive rate of 67% (24 cases) in R. tsutsugamushi and 33% (12 cases) in R. typhi and two cases were seropositive to Korean Hemorrhagic Fever. 3) Clinical pictures of Tsutsugamushi disease were characterized by fever (88%), chills (71%), headache (71 %) and abdominal pain (50%) but were less severe in R. typhi as fever in 83% of cases, chills 67% and headache 67%. 4) On physical examination, abdominal tenderness (54 %), fever (38%), CVA tenderness (29%), tachycardia (25 %) and eschar (13%) were found but were less severe in R. typhi as abdominal tenderness in 25% of cases, fever 25%, CVA tenderness 17% and tachycardia 17%. 5) On laboratory examination, a left shift of leukocytes, atypical lymphocytes, anemia, microscopic hematuria and proteinuria were found. Blood chemistry findings were characterized by increased SGOT & SGPT and increased CPK & LDH. The chest X-ray revealed interstitial pneumonia in nine cases (25%).