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백서 두개골에 형성된 골 결손부 크기에 따른 골 치유과정에 대한 조직학적 연구
윤도철,김경욱,임창준,김종여 단국대학교 치의학연구소 1994 논문집 Vol.6 No.1
The author made calvarial defects of different sizes in rat to study the effect of defect size on healing process. Experimental animals were sacrified at 3 days, 1 week, 2, 4, 6 weeks. The specimens were examed under light microscope with Hematoxlin-Eosin and modified Gomori's trichrome stain, and under fluorescent microscope after glinding the specimens. The results were as follows. 1. 4㎜-diameter calvarial defects healed about 70% after 6 weeks. 2. Lamellated bone trabecules were seen in 6㎜-diameter calvarial defects after 4 weeks, and the small specules of bone and marrows were observed after 6 weeks. 3. 10㎜-diameters calvarial defects healed about 50% and incomplete interconnection of the lamellated bone trabecules were observed after 6 weeks. 4. Under fluorescent microscope, about 4㎜-long bone regeneration could be seen in most of the defects.
백서 두개골에 형성된 골 결손부 크기에 따른 골 치유과정에 대한 조직학적 연구
윤도철(Do Cheol Yun),이재훈(Jae Hun Lee),임한욱(Han Wook Lim),김기환(Ki Whan Kim),김경욱(Kyung Wook Kim) 대한구강악안면외과학회 1995 대한구강악안면외과학회지 Vol.21 No.1
The author made calvarial defects of different sizes in rat to study the effect of defect size on healing process. Experimantal animals were sacrified at 3 days, 1 week, 2, 4, 6 weeks. The specimens were examed under light microscope with Hematoxlin-Eosin and modified Gomori s trichrome stain, and under fluorescent microscope after glinding the specimens. The results were as follows. 1. 4mm-diameter calvarial defects healed about 70% after 6 weeks. 2. Lamellated bone trabecules were seen in 6mm-diameter calvarial defects after 4 weeks, and the small specules of bone and marrows were observed after 6 weeks. 3. 10mm-diameters calvarial defects healed about 50% and incomplete interconnection of the lamellated bone trabecules were observed after 6 weeks. 4. Under fluorescent microscope, about 4mm-long bone regeneration could be seen in most of the defects.