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SD계 랫트와 db/db 마우스에서 Curcuma longa L. 가 비만과 인슐린저항성에 미치는 영향
유미경 ( Mi Kyoung You ),김민숙 ( Min Sook Kim ),류동영 ( Dong Young Rhyu ),김현아 ( Hyeon A Kim ) 한국식품저장유통학회(구 한국농산물저장유통학회) 2013 한국식품저장유통학회지 Vol.20 No.1
In this study, the effect of Curcuma longa L. on ibesity and insulin resistance was investigated in animals fed a moderate high fat diet. The animals used in this study were normal weight Spargue-Dawley (SD) rats and type 2 diabetic obese db/db mice. Accumulation of abdominal adipose tissue and weight gain were inhibited in the animals fed the C. longa extract. C. longa decreased fasting insulin and HOMA-IR in the SD rats, and effectively decreased blood glucose and hemoglobin Alc in db/db mice. C. longa decreased serum free fatty acid level in the SD rats. FFA in db/db mice fed C. longa tended to decrease. C. longa significantly decreased serum triglyceride level. Our results collectively represent that C. longa prevented fat accumulation and insulin resistance in both nomal weight SD rats and type 2 diabetic obese db/db mice fed a moderate high fat diet.