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이종곤(Jong Kon Lee),이병삼(Byung Sam Lee),신옥식(Ok Shick Shin),신규창(Kyu Chang Shin),오용구(Yong Ky Oh),기세길(Se Gil Ki) 대한내과학회 1991 대한내과학회지 Vol.41 No.4
N/A Tsutsugamushi disease is an acute febrile disease which is characterized by fever, headache, rash, and eschar. In Korea, there has been an increasing concern over rickettsiosis since Tsutsugamushi disease among Koreans was first reported in 1986. We experienced 75 cases of Tsutsugamushi disease that occurred during the periods of October-November, 1989, 1990. They which were confirmed by indirect immunofluorecent antibody test and their clinical findings were analized. Of 75 cases, 28 were males and 47 were females. The mean age was 50 years. The main symptoms and signs were headache, myalgia, fever, rash, and eschar. Characteristic laboratory findings included hypoalbuminemia, elevation of SGOT, proteinuria and interstitial pneumonia on chest X-ray. The mean duration of defervescence of fever was l. 4 days with tetracycline therapy and 1,25 days with chloramphenicol therapy. All cases improved and there were no recurrences.