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        조기파막 환자의 혈중 중 , Esstadiol-17B 및 Progesterone치의 동태에 관한 연구

        신영실(YS Shin),이진용(JY Lee) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.1

        Premature rupture of membrances is very important because of its association with prematurity cord prolapse, chorioamnionitis high prenatal mortality and at times serious maternal morbidity. The purpose of this study is to measure the serum copper, estradiol-17B and progesterone levels in patients with and without premature rupture of membranes and to evaluate the relationship between copper, steriod hormone and premature rupture of membranes. The results of the study are as follows; 1. serum copper levels in patients with PROM at term range from 204.6 to 281.4 ug/100ml with a mean+-S.E.M of 241.3+-22.3ug/100ml, whereas in the corresponding control group of normal term pregnancy from 224.9 to 299.9ug/100ml with a mean+-S.E.M of 255.1+-19.2ug/100ml. serum copper levels in patients with PROM significantly lower than in those with control group. 2. Concentration of serum estradiol-17B and progesterone in patients with PROM range from 14.36 to 36.88ng/ml with a mean +-S.E.M of 25.88+-7.00ng/ml and from 90.60 to 191.00ng/ml with a mean +-S.E.M of 141.40+-25.95ng/ml respectively, whereas in corresponding control group range from 15.04 to 44.16ng/ml with a mean +- S.E.M of 30.12+-7.93ng/ml respectively. serum estadiol-17B and progesterone levels are significantly lower in patients with PROM at term as compared with a control group. 3. There is little significant relationship between copper and steroid hormone in both group.

      • KCI등재

        난소에 발생한 내배엽동 종양 1예

        신면우(MW Shin),신희철(HC Shin),남주현(CH Nam),박세웅(SW Park),이건용(KY Lee),신영실(YS Shin) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.5

        Endodermal sinus tumor is a rare and highly malignant gonadal neoplasm. Schiuer, in 1939 recongnized the unigue microscopic charcteristics of this neoplasm peculiar epithelial and endothelial relationships resembling mesonephric glomeruli and termed nesonepheoma ovarii, But Teilum in 1959 recongnized the histology to be reminiscent of yolk sac and allaxtaic interreationships in the rat placenta so called endodermal sinus of Dural and termed endodermal sinus tumor of the ovary. Until now, approximately 150 cases of pure endodermal sinus tumors or mixed germ cell tumors with endodermal sinus with endodermal sinus pattern have been reported. In this reports We present a patients with an endodermal sinus tumor of the ovary and review the classical and current word literature on this tumor

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