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김희성 ( Hee Seong Kim ),송명곤 ( Myung Gon Song ),김용욱 ( Yong Wook Kim ),김경심 ( Kyoung Sim Kim ),김은영 ( Eun Young Kim ),김령 ( Young Kim ),장해인 ( Hae In Jang ),조형민 ( Hyung Min Cho ) 대한천식알레르기학회(구 대한알레르기학회) 2017 Allergy Asthma & Respiratory Disease Vol.5 No.5
Purpose: The aim of this study was to evaluate whether or not the early use of steroid is useful for treating Mycoplasma pneumoniae pneumonia. Methods: A prospective study was conducted on 85 patients with M. pneumoniae pneumonia admitted to Gwangju Christian Hos-pital between September 2015 and April 2016. A total of 85 patients were enrolled. Of these, 33 were treated with steroids (methyl-prednisolone 1 mg/kg/day), while 52 were not; both were treated with macrolides. The overall duration of fever was compared be-tween the 2 groups and findings on chest radiographs were evaluated for their deterioration. Results: The duration of fever after admission (1.36±0.92 days vs. 2.17±1.30 days, P=0.003) and the overall duration of fever (4.42±2.13 days vs. 6.07±2.59 days, P=0.003) were significantly lower in the steroid group. The duration of fever before admission was not different between the steroid and macrolide groups (3.06±1.74 days vs. 3.90±2.21 days, P=0.068). On chest radiographs taken 3 days later, 1 of 33 patients in the steroid group and 5 of 50 patients in the macrolide group worsened, although there was no statistically significant difference between the 2 groups (P=0.395). There was no significant difference in the duration of hospi-talization between the 2 groups (6.72±1.54 days vs. 6.92±1.87 days, P=0.618). Conclusion: Early administration of steroids on patients with M. pneumoniae pneumonia reduced the duration of fever, but there was no difference in duration of admission and x-ray deterioration. (Allergy Asthma Respir Dis 2017;5:280-286)