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배경동(Kyung-Dong Bae),류호완(Ho-Wan Ryu),김윤재(Yun-Jae Kim),오영진(Young-Jin Oh) 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.2015 No.11
Complex crack is the form of crack existing through-wall crack and surface crack at the same time. Complex crack is mainly caused by PWSCC phenomenon in pipe with overlay maintenance welding. Unlike through-wall cracked pipe and surface cracked pipe, complex cracked pipe has a complex behavior. Generally, through-wall cracked pipe which has thickness of complex cracked pipe ligament is used to evaluate complex cracked pipe. However, this method has conservative results in limit load evaluation (netsection collapse load). Therefore, in this paper, equivalent thickness concept is introduced in method for evaluation complex cracked pipe and this method using equivalent thickness is validated.
복합하중이 작용하는 감육피더관의 굽힘각도별 한계하중 변화
배경동(Kyung Dong Bae),제진호(Jin Ho Je),김윤재(Yun Jae Kim) 대한기계학회 2011 대한기계학회 춘추학술대회 Vol.2011 No.10
Flow Accelerated Corrosion (FAC) during in-service conditions produces local wall-thinning in the feeder pipes of CANDU. The Wall-thinning in the feeder pipes is main degradation mechanisms affecting the durability of piping systems. This paper discusses effect of band angle in feeder pipe under combined loading condition. Based on limit load analysis, this paper provides tendency of limit load for wall-thinned feeder pipes under combined bending and internal pressure. The limit loads are determined from limit analysis based on elastic-perfectly-plastic materials using the large geometry change.
파단전 누설 평가를 위한 Ramberg - Osgood 상수 결정법
배경동(Kyung Dong Bae),류호완(Ho Wan Ryu),김윤재(Yun Jae Kim),김진원(Jin Weon Kim),김종성(Jong Sung Kim),오영진(Young Jin Oh) 대한기계학회 2015 大韓機械學會論文集A Vol.39 No.7
본 논문은 이전 연구에서 제시한 여러 가지 Ramberg-Osgood 상수 결정법을 비교하여 파단전 누설평가에 사용되기 가장 적합한 상수 결정법을 선정하였다. 비교에 사용한 재료는 운전온도인 316℃에서 실험한 SA312 TP316 과 SA508 Gr.1a 이. 상수 결정법을 선정하기 위해 실제 응력-변형률 데이터를 모두 이용하는 증분 소성 이론과 Ramberg-Osgood 상수를 이용하는 변형 소성이론을 유한요소 해석에 적용하여 계산한 J 적분과 균열 열림 변위를 비교하였다. 비교 결과에서 증분 소성 이론 결과와 가장 잘 일치하는 상수 결정법을 최종적으로 파단전 누설 평가에 적합한 방법으로 선정하였다. In this study, a method for determining Ramberg?Osgood constants for leak-before-break evaluation was investigated. The Ramberg?Osgood constants were calculated for SA312, TP316, and SA-508 Gr.1a in an operating temperature of 316 oC. Incremental plasticity, using stress?strain data obtained from experiment, and deformation plasticity, using the Ramberg-Osgood constants, were considered in a finite element analysis. Using incremental plasticity and deformation plasticity, J-integrals and crack opening displacement values were calculated and compared. By comparing the results of incremental plasticity and deformation plasticity, a suitable method for determining Ramberg?Osgood constants for leak-before-break evaluation was confirmed.
The Evolution and Value of Diphtheria Vaccine
Bae, Kyung Dong(배경동) 한국생물공학회 2011 KSBB Journal Vol.26 No.6
This review article provides an overview of the evolution of diphtheria vaccine, its value and its future. Diphtheria is an infectious illness caused by diphtheria toxin produced by pathogenic strains of Corynebacterium diphtheriae. It is characterized by a sore throat with membrane formation due to local tissue necrosis, which can lead to fatal airway obstruction; neural and cardiac damage are other common complications. Diphtheria vaccine was first brought to market in the 1920s, following the discovery that diphtheria toxin can be detoxified using formalin. However, conventional formalin-inactivated toxoid vaccines have some fundamental limitations. Innovative technologies and approaches with the potential to overcome these limitations are discussed in this paper. These include genetic inactivation of diphtheria toxoid, innovative vaccine delivery systems, new adjuvants (both TLRindependent and TLR-dependent adjuvants), and heat- and freeze-stable agents, as well as novel platforms for producing improved conventional vaccine, DNA vaccine, transcutaneous (microneedle-mediated) vaccine, oral vaccine and edible vaccine expressed in transgenic plants. These innovations target improvements in vaccine quality (efficacy, safety, stability and consistency), ease of use and/or thermal stability. Their successful development and use should help to increase global diphtheria vaccine coverage.
The Evolution and Value of Diphtheria Vaccine
배경동,Bae, Kyung-Dong The Korean Society for Biotechnology and Bioengine 2011 KSBB Journal Vol.16 No.3
This review article provides an overview of the evolution of diphtheria vaccine, its value and its future. Diphtheria is an infectious illness caused by diphtheria toxin produced by pathogenic strains of Corynebacterium diphtheriae. It is characterized by a sore throat with membrane formation due to local tissue necrosis, which can lead to fatal airway obstruction; neural and cardiac damage are other common complications. Diphtheria vaccine was first brought to market in the 1920s, following the discovery that diphtheria toxin can be detoxified using formalin. However, conventional formalin-inactivated toxoid vaccines have some fundamental limitations. Innovative technologies and approaches with the potential to overcome these limitations are discussed in this paper. These include genetic inactivation of diphtheria toxoid, innovative vaccine delivery systems, new adjuvants (both TLR-independent and TLR-dependent adjuvants), and heat- and freeze-stable agents, as well as novel platforms for producing improved conventional vaccine, DNA vaccine, transcutaneous (microneedle-mediated) vaccine, oral vaccine and edible vaccine expressed in transgenic plants. These innovations target improvements in vaccine quality (efficacy, safety, stability and consistency), ease of use and/or thermal stability. Their successful development and use should help to increase global diphtheria vaccine coverage.
감육이 발생한 중수로 피더관의 굽힘각도에 따른 한계내압의 변화
배경동(Kyung Dong Bae),제진호(Jin Ho Je),김윤재(Yun Jae Kim) 대한기계학회 2011 대한기계학회 춘추학술대회 Vol.2011 No.4
캐나다형 중수로에 설치된 피더관은 유동가속부식에 의하여 감육현상이 발생된다. 피더관에서의 감육발생현상은 배관구조의 구조적 건전성을 감소시키는 주된 원인이다. 본 논문에서는 유한요소해석을 이용하여 감육이 발생한 피더관의 구조적 신뢰성을 평가하였다. 유한요소해석에 기초하여 각 피더관의 한계내압을 구하고 그 결과를 이용하여 굽힘각도에 따른 한계내압의 변화를 관찰하였다. 한계하중은 대변형해석 조건과 탄성완전소성물성치 가정을 이용하여 수행되었다. Flow Accelerated Corrosion(FAC) during in-service conditions produces local wall-thinning in the feeder pipes of CANDU. The Wall-thinning in the feeder pipes is main degradation mechanisms affecting the durability of piping systems. Based on finite element limit analysis, this paper provides the effect of band angle about wall-thinned feeder pipes under internal pressure. The limit loads are determined from limit analyses based on elastic-perfectly-plastic materials using the large geometry change.
굽힘각도를 고려한 원형 감육이 발생한 중수로 피더관의 한계하중
배경동(Kyung Dong Bae),제진호(Jin Ho Je),김종성(Jong Sung Kim),김윤재(Yun Jae Kim) 대한기계학회 2012 大韓機械學會論文集A Vol.36 No.3
캐나다형 중수로에서 피더관은 중수로 압력관에 중수를 공급하고 가열된 중수를 증기발생기로 보내는 배관으로 가동 중에 유동 가속 부식현상에 의해 감육이 발생한다. 배관에 감육이 발생하게 되면 배관의 건정성이 떨어진다는 결과는 앞선 연구에서 확인하였다. 본 논문에서는 45 도와 60 도의 굽힘각도를 갖는 피더관의 한계하중을 제시하고 제시된 연구결과를 바탕으로 임의의 굽힘각도를 갖는 피더관에서 감육이 발생했을 경우의 한계하중을 예측 할 수 있는 식을 제시하였다. 본 연구에서는 유한요소해석을 통하여 굽힘 하중과 내압을 받는 경우에 대하여 연구를 진행하였고 특히 굽힘 하중의 경우 면내열림 방향과 면내 닫힘 방향으로 나누어 진행하였다. 재료는 대변형 효과를 고려하고 탄성-완전소성 재료로 가정하였다. In CANDU, feeder pipes supply heavy water to pressure tube and steam generator. Under service conditions, Flow-Accelerated Corrosion (FAC) produces local wall-thinning in the feeder pipes. The wall-thinning in these pipes affects the integrity of the piping system, as verified in previous research. This paper provides limit loads for wallthinned feeder pipes with 45° and 60° bend angles, and proposes an equation that predicts the limit loads for wallthinned feeder pipes with arbitrary bend angles. On the basis of finite element limit analyses, limit loads are obtained for wall-thinned feeder pipes under in-plane bending and internal pressure. There are two cases of in-plane bending: the in-plane closing direction and the in-plane opening direction. The material is considered the effect of the large deformation, so an elastic-perfectly-plastic material is assumed in the calculations.