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수정땀띠 양상의 물집병변으로 나타난 간 이식 후 급성 이식편대숙주병
배경남 ( Kyungnam Bae ),신기혁 ( Kihyuk Shin ),양민영 ( Minyoung Yang ),이원구 ( Won-ku Lee ),김태욱 ( Taewook Kim ),김훈수 ( Hoon-soo Kim ),고현창 ( Hyun-chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon-bum Kim ),김우일 ( Woo-il 대한피부과학회 2020 대한피부과학회지 Vol.58 No.5
Acute graft-versus-host disease (GVHD) is a common complication associated with bone marrow transplantation. In the rare cases where it occurs after solid organ transplantation, including that of the liver, pancreas, or heart, it often has fatal outcomes. A 50-year old man developed whole-body flaccid vesiculobullous eruption 6 weeks after living donor liver transplantation. Skin biopsy revealed epidermal necrosis with vacuolization of the basal layer and lymphocytic infiltration in the dermis. Stomach erosions were found during an endoscopy, and a concurrent biopsy revealed severe epithelial necrosis. GVHD was diagnosed, with mixed chimerism confirmed using short tandem repeat testing. Immunosuppressive agent therapy was instituted, but the patient expired from hematologic complications and brain damage 6 weeks after treatment initiation. Skin lesions in GVHD generally appear with erythematous maculopapular eruption, but some atypical cutaneous manifestations could be unnoticed by physicians. This report describes miliaria crystallina-like eruption of acute GVHD after liver transplantation. (Korean J Dermatol 2020;58(5):340∼343)
피어싱에 의한 귀 가성림프종 4예: 임상적 특징 분석 및 문헌고찰
배경남 ( Kyungnam Bae ),신기혁 ( Kihyuk Shin ),고현창 ( Hyun-chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon-bum Kim ),김훈수 ( Hoon-soo Kim ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.7
Cutaneous pseudolymphoma, also referred to as cutaneous lymphoid hyperplasia or lymphocytoma cutis, is an uncommon lymphoproliferative condition. Most lesions are idiopathic in origin; however, triggers such as tattoos, acupuncture, or venipuncture are known to be associated with pseudolymphomas. Owing to the widespread popularity of cosmetic piercings, post-piercing pseudolymphomas are being reported in recent times. Anatomically, most lesions appear on the ears and present with a variety of morphological features, although diagnosis is based on distinctive clinical findings. In this case series, we report four cases of post-piercing pseudolymphoma on the earlobe together with a literature review. We emphasize close and careful monitoring to differentiate this rare condition from other lesions of the earlobe. In view of the diverse clinical presentations and treatment approaches available for pseudolymphomas, we highlight some preliminary clinical indicators to enable early diagnosis and prompt treatment of this condition. (Korean J Dermatol 2021;59(7):544∼549)