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Mycobacterium chelonae에 의한 피부감염
한희진 ( Han Hui Jin ),강권수 ( Kang Gwon Su ),이보현 ( Lee Bo Hyeon ),박천욱 ( Park Cheon Ug ),이철헌 ( Lee Cheol Heon ),유종우 ( Yu Jong U ) 대한피부과학회 2004 대한피부과학회지 Vol.42 No.3
Mycobacterium chelonae is a rapidly growing atypical mycobacteria that can cause both systemic and cutaneous infections as a human pathogen. This saprophyte is ubiquitous in the environment and has been found in water, soil, and dust particles Clarithromycin is a highly specific drug against M. chelonae. A 53-year-old man had a nodule on the dorsum of his right hand that had developed in 3~4 months. The lision was a slightly tender 2.0×1.5㎝ erythematous nodule and had an overlying ruptured pustule. Culture demonstrated atypical mycobacterim, with a polymerase chain reaction (PCR) which confirmed M. chelonae. (Korean J Dermatol 2004;42(3):320~323)
아토피 피부염 환자에서 식품 알레르기에 대한 CAP-RAST FEIA와 개방 경구유발시험에 관한 연구
전현진 ( Jeon Hyeon Jin ),방형돈 ( Bang Hyeong Don ),김광호 ( Kim Gwang Ho ),박천욱 ( Park Cheon Ug ),김광중 ( Kim Gwang Jung ),이철헌 ( Lee Cheol Heon ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.8
N/A Background : The role of dietary factors in atopic dermatitis has been the subject of debate for several decades. Recently it has received convincing support from a double-blind controlled trial of an exclusion diet, showing benefit from careful avoidance of egg and milk in a group of atopic children. Object : The purpose of this study was to determine the prevalence of specific food allergies in Korean atopic dermatitis and the potential utility of the Pharmacia CAP-RAST FEIA in the diagnosis of food allergy. Methods : One hundred ten patients with atopic dermatitis were evaluated for food hypersensitivity by history, skin prick test, CAP-RAST FEIA, and open food challenge test(OFCT). Results : 1) The prevalence of specific food allergies in the study population was 28.2% in history and 18.2% in CAP-RAST FEIA and OFCT. 2) The frequent food allergens were milk, egg, peanut, and wheat. 3) There was no correlation between the clinical severity of atopic dermatitis and CAP-RAST FEIA and OFCT results. 4) Plasma eosinophil and IgE levels were correlated with CAP-RAST FEIA results, but not OFCT results. 5) According to the history, 31 atopic dermatitis patients answered that their dermatitis was related to food, and of the 31 patients, positive reactions to prick test and CAP-RAST FEIA were observed in 8 and 22 patients, respectively. Among the other 79 patients who answered that there was no relation between atopic dermatitis and food, 14 patients reacted positively to prick test and 47 patients showed positive result to CAP-RAST FEIA. Conclusion : The CAP-RAST FEIA provides standardized measurement of food specific IgE antibodies which may be useful to diagnose food allergy in atopic dermatitis. (Korean J Dermatol 2003;41(8) : 1034~1040)