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RISS 인기검색어
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- 저자 : 박경완 ( Kyoungwan Park ) (검색결과 4 건)
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군견에서 분리한 Enterococcus faecalis, E. faecium의 항생제 내성 연구
박경완 ( Kyoungwan Park ),주영훈 ( Younghoon Joo ),조성범 ( Sungbum Cho ),방기만 ( Kiman Bang ),고명식 ( Myeongsik Ko ),유건주 ( Gunju Yoo ) 국군의무사령부 2017 대한군진의학학술지 Vol.48 No.1
Objective: Investigate antimicrobial resistance of enterococci isolated from various group of military working dogs(MWDs) to understand their characteristics and the differences between isolates from different groups. Methods: Fecal samples of military working dogs were collected from military working dog training center located in Chuncheon, Korea. Samples were collected by using sterile material and transported to laboratory within 12hrs. Species was confirmed by polymerase chain reaction. Antimicrobial susceptibility test was performed on E. faecalis, E. faecium, and other unidentified Enterococcus spp. isolates using disk diffusion method against 12 antibiotics. Results: First, in cohort study, we collected 193 feces samples from three group of puppy dogs and 200 Enterococcus spp. (149; 74.50% E. faecalis, 45; 22.50% E. faecium, 6; 3.00% other Enterococcus spp.) were isolated from this samples. All 200 isolates were susceptible to ampicillin, amoxicillin-clavulanic acid, chloramphenicol, imipenem. Antimicrobial resistance against aminoglycosides and ciprofloxacin of the isolates was increased with growth of the puppy dogs. In cross sectional study, total 137 samples including 127 feces and 10 soil samples were collected. 44 E. faecalis, 50 E. faecium, and 19 species unidentified Enterococcus were isolated from those samples. In case of refresher training dogs, the isolation rate of E. faecalis was high shortly after entering training center, but the isolation rate of E. faecium tended to increase immediately before leaving. Most antimicrobial resistance rates were higher in enterococci isolated from MWDs served MWDs training center than in enterococci isolated from refresher training MWDs served other field troops. Conclusion: Continuous monitoring of antimicrobial resistance is needed to consider the possibility of exposure to antibiotic-resistant bacteria in soldiers who live with dogs and select appropriate antibiotics for MWDs.
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박경완(KyoungWan Park),이성재(Seongjae Lee),신민철(Mincheol Shin),이일항(El-Hang Lee),김주진(Ju-Jin Kim),이후종(Hu Jong Lee) 한국진공학회(ASCT) 1993 Applied Science and Convergence Technology Vol.2 No.4
전자의 파동성에 기인하는 여러가지 양자간섭 현상을 연구하기 위하여, 금속의 미세고리구조를 제작하였다. 전자의 양자간섭과 가간섭 역충돌 효과에 의한 자기저항의 진동현상이 관측되었으며, 자기저항의 비주기 섭동 현상과 비국재현상도 관찰되어 중시적 전기 전도도의 일반식에 의하여 설명되었다. 또한 AlGaAs/GaAs의 이차원 전자가스층을 이용한 고리구조도 제작되어, 양자 효과와 탄동적 수송의 영역에서 자기저항이 측정되었다. We have fabricated metal-based Aharonov-Bohm ring structures by using electron beam lithography and lift-off techniques and examined various quantum interference phenomena resulting from wave natures of electrons. Oscillations of magnetoresistance were observed at low temperatures, which we attribute to quantum interference and coherent back scattering effect of normal electrons. The intensity of aperiodic fluctuation was measured and explained by the general formula of the conductance fluctuation. Non-local behavior of the electron transport involving the reciprocity relation in the magnetoresistance was seen in the ring structures. Also, mesoscopic rings from the modulation-doped AlGaAs/GaAs heterostructures have been fabricated by using electron beam lithography and chemical wet etching techniques. The magnetoresistance has been measured at 10 mK in order to examine the transport characteristics in the regime where the quantum effects and the ballistic transport dominate.
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식육에서 항생제 잔류 허용 기준에서의 생물학적 활성을 이용한 잔류 항생 물질 검출 개선
이동하 ( Dong Ha Lee ),정상영 ( Sang Young Jung ),박경완 ( Kyoungwan Park ),홍성탁 ( Sung Tak Hong ),박승춘 ( Seung Chun Park ) 국군의무사령부 2018 대한군진의학학술지 Vol.49 No.1
Objectives : The European economic community four plate test(EEC 4-plate test) has been used for monitoring antibacterial drug residue in meat by food investigation unit. However, the sensitivity of the current assay is insufficient to detect some residual antibacterial agents over the level of maximum residue limits(MRLs). This study was performed to investigate the limit of detection(LOD) of eight families of antibacterial agents including florfenicol, ceftiofur, cefquinome and to suggest the improved biological assay that can detect some antibacterial agents which are undetectable at the level of MRLs by the current assay. Methods : Bacillus subtilis BGA spore suspension, Micrococcus luteus ATCC 9341, and Escherichia coli ATCC 11303 were inoculated in 5 different media. Results : The test agar with streptomycin for detection of cefquinome showed four times higher sensitivity(0.2 mg/kg at bacillus subtilis pH 6.0 plate, 0.05 mg/kg at micrococcus luteus pH 8.0 plate) compared to original method. Conclusions : This study has shown that new high sensitivity EEC 4-plate test using combinations of cefquinome with streptomycin through antibiotic synergism improves the detection capabilities of various antibacterial agents.
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