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한국인에서 안면 주름과 양성교근비대증에서의 A형 보툴리눔 독소 치료
노낙경 ( Nark Kyoung Rho ),김혜성 ( Hai Sung Kim ),김윤성 ( Yoon Seong Kim ),김연진 ( Yun Jin Kim ),김종혁 ( Chong Hyeok Kim ),민복기 ( Pok Kee Min ),서석배 ( Suk Bae Suh ),이강석 ( Kang Seok Lee ),이상주 ( Sang Ju Lee ),이우선 ( 대한피부과학회 2010 대한피부과학회지 Vol.48 No.10
Background: The utilization of botulinum toxin has rapidly expanded into various aesthetic applications. Achieving success with the aesthetic use of neurotoxins depends on several factors, including an understanding of the anatomy, the methods of dilution and the injection technique. Any guidelines representing a consensus for aesthetic treatments using botulinum toxin type A (BTA) have not been published in Korea. Objective: We wanted to provide consensus recommendations on the treatment of facial wrinkles and benign masseter hypertrophy using BTA in Korean patients. Methods: A panel of experienced Korean dermatologists was convened to develop a clinical consensus. The clinical consensus was comprised of the recommendations of the panel and the guidelines on general issues, such as the reconstitution and handling of the BTA, the procedural considerations, the dosing and injection-site standardizations, and the prevention and treatment of unwanted effects. Specific recommendations were provided according to the area of treatment, including glabellar lines, horizontal forehead lines, lateral periorbital wrinkles and benign masseter hypertrophy. Results: The recommended final concentration of BTA was 50 units/ml (5 units/0.1 ml) after reconstitution with physiologic saline. For glabellar lines, the members recommend three injection points (a total of 8 units). For forehead wrinkles, the members recommend nine injections in two rows into the frontalis with 1 unit/point. For crow`s feet, the members recommend three injections per side (7 units/side) at the lateral part of the orbicularis oculi. For benign masseter hypertrophy, three injections per side (24~30 units/side) were recommended. Conclusion: These consensus recommendations will provide a framework for Korean dermatologists who wish to perform safe and efficacious injection of BTA for facial rejuvenation. (Korean J Dermatol 2010;48(10):823~831)
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