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        숫 흰쥐에 있어서 거세및 Testosterone Propionate 투여가 체성장 및 내분비선 발육에 미치는 영향

        정기연,정영채,김창근 ( Kie Youn Chung,Yung Chai Chung,Chang Keun Kim ) 한국축산학회 1979 한국축산학회지 Vol.21 No.1

        This experiment was conducted to investigate the effect of sex hormone treatment on body growth and endocrine glands development in immature rat. One hundred and twenty immature rats, 25 days old weighing 64±2.0㎎, were divided into two groups, control and castration, and divided again into treated and untreated group with testosterone propionate. Each group was composed of 30 rats. The body weight was measured weekly from the beginning of treatment to 63 days after treatment and for the changes in endocrine glands, the animals were sacrificed 7, 21, 35, 49 and 63 days after treatment respectively. The result obtained were as follows. 1. The changes in body weight during the experiment period were not appeared distinctly differences between two groups, although the control was higher than the treated groups. 2. The body lengths were not significant differences between treated-groups, but the body length increased with the similar patterns in all groups in the whole periods. 3. The hypophysis weight was appeared to significant differences from 35 days after treatment of testosterone propionate. Generally, the weight of castrated-group was distinctly heavier than that of uncastrated-group (P $lt; 0.0l). 4. The testis weight in uncastrated-groups was highly decreased in the. treated-rats than the untreated-rats and the differences between these groups were highly significant (P$lt;0.01). 5. The seminal vesicle weight of TP-treated rat in control group was the largest in 4 groups and the seminal vesicle was almost disappeared in non-treated rat of the castrated group. 6. The weight of adrenal gland of the non-TP in castrated group was increased distinctly at 49 and 63 days after treatment but no significant differences were recognized among the other three groups.

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