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안병철(Byeong Cheol Ahn),이양일(Yang Il Lee),최성곤(Seng Gon Choi),권중구(Joong Gu Kwen),이창형(Chang Hyung Lee),윤영미(Young Mee Yun),탁원영(Won Young Tak),관규식(Kyu Shik Kwak),최용환(Yong Hwan Choi),정준모(Joon Mo Chung) 대한내과학회 1994 대한내과학회지 Vol.46 No.1
N/A Background: Even though the hepatoma rupture has been known to be one of the fatal complications of hepatoma, the detailed studies on it were few in Korea. Methods: In order to investigate whether the he- patoma rupture can affect the survival of hepatoma patients or not, and also which factors can influence the prognosis of patients with hepatoma rupture, we studied 67 patients with hepatoma rupture and 74 age-matched hepatoma patients without rupture. Results: 1) Incidences of cirrhosis, ascites, hepatic encephalopathy, and unfavorable grade of Child`s classification were more prevalent in rupture group than in control group. Rupture group showed lower mean values of hemoglobin, prothrombin time, total protein and albumin, and higher mean level of GOT than those of control group. 2) But, there was no significant difference in survival time between rupture group and control group. 3) In rupture group, the survival time was more prolonged in patients with more favorable grade of Child`s classification, The survival time tended to be more prolonged in patients treated with TAE method than those managed with conservative treatment, but unfortunately, the results was statistically not significant, 4) In control group, survival time was prolonged in patients with more favorable grade of Child's classification and in those treated with TAE method. Conclusion: Treatment modality and liver status are most significant prognostic factors in hepatoma rupture patients and TAE method should be considered.