http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 고수희 ( Soo Hee Go ) (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Axillary LN meta가 있는 유방암에서 액와 림프절의 FDG uptake가 가지는 임상적 의미
고수희 ( Soo Hee Go ),서형일 ( Hyung Il Seo ),이지연 ( Jee Yeon Lee ),정윤주 ( Youn Joo Jung ) 대한임상종양학회 2010 Korean Journal of Clinical Oncology Vol.6 No.2
Purpose: 18F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography(18F-FDG PET/CT) has been recommended as a diagnostic modality for preoperative staging of breast cancer. But, the information for FDG uptake on axillary lymph node(ALN) is not sufficient. Authors investigated the FDG uptake on ALN in preoperative 18F-FDG PET/CT and tumor characteristics to figure out their association and its clinical significance. Materials and Methods: From Jan. to Dec. 2007, 176 patients had been performed preoperative 18F-FDG PET/CT. Only sixty-five cases were confirmed as ALN metastasis in pathologic report. Thirty-one patients with high FDG uptake of ALN (SUVmax>1.0) and thirty-four with low FDG uptake (SUVmax≤1.0) in 18F-FDG PET/CT were classified as group A and B, respectively. Results: The FDG uptake of ALN showed significant relationship with poor prognostic factors of primary tumor(worse histologic grade, negativity of estrogen and progesterone receptor, positivity of p53 and c-erbB2 gene, tumor necrosis, lymphovascular invasion) and ALN metastasis. In multivariate analysis, FDG uptake of ALN showed larger tumor size (p=0.001), higher Ki-67 (p=0.004), bigger and more metastatic ALN (p=0.017, <0.001) compared to low FDG uptake of ALN. The cut-off values of high FDG uptake were 1.85 cm of primary tumor size, 17.5% of Ki-67, 2.5 and 0.95 cm of number and size of metastatic ALN. Conclusion: The most valuable sensitivity and specificity of FDG uptake in metastatic ALN were shown when the number and size of ALN was more than 3 or 0.95 cm and they would be large enough to perform ultrasonographyguided biopsy. We recommend preoperative ALN biopsy for the cases of FDG uptake on ALN in preoperative 18FFDG PET/CT and the sentinel lymph node biopsy might be skipped if metastasis is confirmed on biopsy.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
