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강건일 한국약제학회 1984 Journal of Pharmaceutical Investigation Vol.14 No.4
The use of stable isotope compounds in pharmaceutical research was described with recent 33 references, which include synthesis, selected ion monitoring, pharmacokinetics, drug metabolism, and mechanism of drug action.
Tranylcypromine의 겉보기 해리항수(解離恒數) 및 분배계수(分配係數)
강건일,정순영,Kang, Gun-Il,Chung, Soon-Young 대한약학회 1984 약학회지 Vol.28 No.5
The pKa' of tranylcypromine was determined by potentiometric titration and ultraviolet spectrophotometric method and found to be 8.08 and 8.15, respectively. The Papp of tranylcypromine between n-heptane and aqueous buffer solution was measured to be 0.90 at pH 7.48 and 4.50 for Pm. The pKa' of tranylcypromine obtained by means of the partition method was 8.13.