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장철호,정철영 인제대학교 1997 仁濟醫學 Vol.18 No.3
결절성 십이지장염은 일반적으로 내시경 검사상 흔치 않은 소견으로 최근 말기 신장 질환과 연관이 있는 것으로 알려지고 있다. 본 연구는 위내시경 검사상 결절성 십이지장염 소견을 보인 소아들을 대상으로 임상 증상, 동반된 내시경 검사 소견, 조직학적 소견 등을 조사하였다. 결절성 십이지장염은 소아에서 비교적 흔히 관찰되는 내시경 소견이며, 거의 모든 예에서 조직학적 염증 소견이 관찰되지만 만성 반복성 복통과 같은 임상 증상과의 관련성은 확실하지 않다. Nodular duodenitis is endoscopically characterized by multiple erythematous nodules in proximal duodenum and may represent a valiant of duodenal inflammation. This study examines the incidence, clinical presentation, endoscopic finding, and histologic feature of nodular duodenitis in 91 children who presented with gastrointestinal symptoms. Endoscopically, in addition to nodular duodenitis, esophagitis was found in 6% of patients and gastritis in 33%. Histology of duodenal nodules revealed chronic inflammation in 91% of patients, lymphoid hyperplasia in 6%, and normal mucosa in 3% of patients. We conclude that nodular duodenitis in children is relatively common and is an endoscopically distinct entity that is associated with chronic inflammation.
Hypersensitivity vasculitis의 증례
한세현,장철호 大韓小兒齒科學會 1989 大韓小兒齒科學會誌 Vol.16 No.2
Patients with hypersensitivity vasculitis have purpuric, palpable lesions, most commonly on the lower part of the legs. Systemic involvement, particulary kidney, is found frequently. Etiologic agents that have been implicated include infection, foreign proteins, chemicals, drugs, and a variety of diseases. The mechanism causing tissue damage is thought to be mediated by immune complexes, although specific antigens have only occasionally been unequivocally identified. Treatment includes bed rest, corticosteroid, and sometimes, cytotoxic drugs. A case of hypersensitivity vasculitis in a boy with oral manifestation and skin lesion is presented.
Cavernous Hemangioma of the Tympanic Membrane
장철호,최현석,홍용성,조용범 대한이비인후과학회 2011 Clinical and Experimental Otorhinolaryngology Vol.4 No.2
Cavernous hemangioma seems to most frequently arise in the posterior portion of the external auditory canal. However, they rarely occur in the tympanic membrane. A 49-year-old male patient was referred for evaluation of right-sided pulsatile tinnitus that he’d experienced for the previous 2 years. Temporal bone computerized tomography showed an isolated soft tissue mass just lateral to the tympanic membrane. There was no evidence of bony erosion or middle ear invasion. The patient underwent excision of the mass using a postauricular approach. The mass was removed en bloc and the defect of the tympanic membrane was repaired by tympanoplasty type I. There was no recurrence after 1 year of follow-up.
소아 만성 삼출성 중이염에서 비만세포 Tryptase의 발현
장철호,김영호,정재권 대한이비인후과학회 2002 대한이비인후과학회지 두경부외과학 Vol.45 No.2
Background and Objectives:Mast cells are localized in the midle ear and Eustachian tube. They play a prominent role in the inflamatory and allergic conditions. The purpose of this study is to investigate if different inflamatory reactions depend on whether patients are allergic or not by measuring concentration of the mast cell tryptase that reflects the mast cell activity. :Twenty-five patients with chronic otitis media with efusion (COME) were studied. Thirteen patients were confirmed allergy positive by multiallergosorbent test. Mast cell tryptase in the middle ear efusions was measured using western blotting. Results:Mast cell tryptase was more strongly expressed in the efusions with allergy positive than in the allergy negative (p<0.01). Conclusion:There was a correlation between mast cell tryptase from ME and allergy, so we conclude that allergy plays a role in the pathogenesis of COME. (Korean J Otolaryngol 2002;45:111-3)