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手拈散煎湯液이 Streptozotocin으로 誘發된 實驗動物의 膵臟損傷에 미치는 影響
崔極來,文九,文錫哉 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1
Sujoˇmsan(수점산) is used in treatmint of Bi-Sim-Tong(脾心痛) and pancreatitis. This study has been carried out to investigate effect of Sujoˇmsan extract on analgesia, antiinflammation, complete blood cell count, glucose level, lactate dehydrogenase (LDH) level, amylase level in the pancreatic damage of experimental animal induced by stretozotocin. The result were obtained as follows. 1. On the experiment of analgesic effect of Sujoˇmsan extract, the writhing syndrome induced by acetic acid was reduced by administration of Sujoˇmsan extract. In the pancreatic damage of mice induced by streptozotocin, the writhing symdrome induced by acetic acid was reduced, too. 2. Anti-inflammatory effects were increased by administration of Sujoˇmsan extract on the edema of the hind paw in rats induced by acetic acid. In the pancreatic damage of rats induced by streptozotocin, anti-inflammatory effects were increased, too. 3. In the pancreatic damage of rats induced by streptozotocin, the WBC count, glucose level, LDH level and the amylase level were decreased. but hemoglobin and hicatocrit were increased comparing with control group by administration of Sujoˇmsan extract. According to these results, Sujoˇmsan extract may be used for curing in the pancreatic damage.
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