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      저자 : ( Yulia Venevtseva ) (검색결과 1 건)
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      • Poster Session : PS 0599 ; Critical Care Medicine ; Who and When is at Risk for Acute Coronary Syndrome

        ( Yulia Venevtseva ),( Aleksandr Melnikov ),( Tatiana Gomova ),( Elena Fedotova ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Acute coronary syndrome (ACS) is the most common reason for hospitalization worldwide. We aimed to examine the prevalence of noncardiac comorbidities and time of onset of ACS in a population of patients hospitalized in the Tula Clinical Emergency Hospital in 2013. Methods: The study sample consisted of 345 patients: 123 women (W) aged 48-89 yrs and 222 men (M) 35-86 yrs. In hospital mortality rate was 2.6%. 55 W and 58 M were diagnosed with ST segment elevation, 39 and 54 - with non-ST elevation myocardial infarction and 29 W and 110 M - with unstable angina. All pts were treated noninvasively. Results: The most prevalent comorbidities were excessive weight (66% of W and 55% of M), diabetes mellitus (23.5 and 10.8%) and chronic kidney disease (CKD; 39.8 and 14.0%). The exact time of chest pain onset was available in 77 W and 102 M. Symptom onset rates were calculated according to the hour of the day (circadian rhythm). Peak occurred in the morning hours (6-12 a.m.) with 29.9% in W and 28.4% in M, pain arises at night (0-6 a.m.) in 22.0 and 18.6%. Afternoon symptom onset (0-6 p.m.) was seen in 29.9 and 29.5% and the evening (6-12 p.m.) - in 18.2 and 23.5% of pts. The ACS rhythm depending on age has been seen in the 60-70 yrs in both sexes, in 70-80 yrs W and was lacking in the older ones. Clear rhythm observed in pts having digestive disorders with prevalence of onset in night (W) and afternoon (M). W with CKD had nocturnal and afternoon peaks. The night-time was dangerous for W and M with cerebrovascular disease. Conclusions: Age, gender and comorbidity tend to infi uence the onset of ACS that may be used in clinical practice.

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