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      • Slide Session : OS-GAS-21 ; Gastroenterology : Analysis of Clinical Outcome of Biliary Vs. Non-Biliary Pancreatitis -Audit of 5 Years Experience at Aga Khan University Hospital (AKUH)

        ( Shoukat Ali Amyna Jiwani ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Objective: There is limited knowledge about the outcomes of acute biliary pancreatitis as compared to non-biliary causes. The objective of our study was to audit our experience at Aga Khan University Hospital with a view to summarize the difference between clinical outcomes of biliary vs. non-biliary acute pancreatitis. Material and Methodology: 351 adult patients who presented to AKUH between Jan 2009 and Dec 2013 with acute pancreatitis were included in the study. The data were retrospectively collected on a designed performa. Depending on the underlying etiology, the patients with biliary pancreatitis were compared with non-biliary type in terms of age, gender, co-morbid conditions, severity of the disease, need for intervention(s), need for ICU, length of hospital stay, morbidity, and mortality. Mean and standard deviation were used for continuous variables and chi square test was used for statistical analysis of categorical data. Results: The proportion of biliary vs. non-biliary pancreatitis was similar in our study. Non-biliary acute pancreatitis was more common in younger age (62.4%; p=0.003) and males (60.7%; p=0.001), as compared to biliary group. The proportion of patients with severe pancreatitis (p=0.052), organ failure (p=0.076), infected pancreatic necrosis (0.067), and need for surgical intervention (p=0.06) was comparable in the two groups. The need for ICU stay (p=0.042), and overall mortality rate (1.73% vs. 9.8 %, p=0.002) was higher in the non-biliary group. Conclusion: Non-biliary acute pancreatitis was as common as biliary pancreatitis in our population, but seems to have higher mortality. The work up for non-biliary pancreatitis needs to be standardized.

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