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RISS 인기검색어
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- 저자 : ( Sae Byeol Chol ) (검색결과 1 건)
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( Sae Byeol Chol ),( Kyung Sik Kim ),( Dong Sub Yoon ),( Kwang Hyub Han ),( Woo Jung Lee ),( Byong Ro Kim ),( Jin Sil Seong ),( Jong Tae Lee ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: In cases of advanced hepatocellular carcinoma (HCC), palliative treatment such as transarterial chemoembolization or chemoinfusion (TACE/TACI) and radiation therapy are performed preoperatively. The aim of this study was to evaluate the outcome of these preoperative treatment prior to hepatic resection. Methods: Between January 1994 and May 2007, 16 patients with advanced stage HCC greater than 5 cm in size are treated with TACE/TACI and radiation therapy prior to hepatic resection. The clinicopathologic factors were reviewed retrospectively. Results: Of the sixteen patients, there were fourteen men and two women, and the mean age was 51 years (range 22-70 years). Preoperative TACE/TACI was performed three times in average, and the median radiation dosage was 45 Gy (range 30-68 Gy). Major hepatic resection was performed. The median diameter of tumor on specimen was 9.0 cm. The degree of tumor necrosis was more than 90% in fourteen patients. Median survival time was 13.3 months. Eleven patients were dead due to tumor recurrence (n=8) and hepatic failure (n=2). Five patients had survived more than 2 years and there were two patients who had survived more than 5 years. Conclusions: Although the prognosis of HCC patients who were underwent preoperative combined TACE/TACI and radiation therapy is not satisfactory, some showed long term survival more than 5 years. Further research will be required to examine the survival and disease control impact in a prospective randomized study.
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