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A rare melanoma feature with primary ovarian origin: a case report and the literature review
( Algeri Paola ),( Rota Sonia Maria ),( Carlini Laura ),( Nicoli Elena ),( Caruso Orlando ),( Motta Teresio ) 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.2
Primary ovarian melanoma arising on a mature ovarian cystic teratoma is extremely rare. As best of our knowledge, to date, 49 cases have been reported in literature. Few information was reported about best management and therapy. We present a case occurred in a 69-year-old woman, without symptoms, who come to our unit for stress incontinence. A pelvic mass was detected and, after imaging evaluation, surgery was performed. The diagnosis was ovarian melanoma arose on a mature teratoma. No other adjuvant treatment was proposed after surgery. She died 9 months after the first diagnosis. Primary ovarian melanoma is a definite entity associated with a variable natural history and poor prognosis. Differential diagnosis is a challenge for the pathologist, because it must be differentiated by metastatic melanoma. The corner stone treatment of this disease is surgery; however, chemotherapy, immunotherapy, and target therapy seem to have a role.
Algeri Paola,Nicoli Elena,Rota Sonia Maria,Caruso Orlando,Manfredini Cinzia,Buzzi Antonella 대한산부인과학회 2018 Obstetrics & Gynecology Science Vol.61 No.1
We reported a case of secondary abdominal pregnancy with placental implantation into the fallopian tube, diagnosed at 16 weeks, in a woman admitted to the emergency room complaining of syncopal attacks. The best approach would be termination of the pregnancy, taking into consideration the high risk to the mother and the low possibility of alive and healthy birth. We had to perform an urgent surgical intervention due to the fact that the patient was in a clinically unstable condition, which was related to hemoperitoneum. If placental implantation is on abdominal organs or vessel the best approach would be to ligate the cord and to leave placenta in situ. Taking into consideration the place of placental implant, the removal of the fallopian tube with the placenta was the safest approach in this case. The best and most acceptable form of treatment would be individualized in case of rare form of ectopic pregnancy.
Clelia Callegari,Paola Algeri,Antonella Buzzi,Teresio Motta,Cinzia Manfredini,Sonia Maria Rota 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.6
Endometrial glassy cell carcinoma (EGCC) is a rare neoplasm, accounting for 0.5% of the carcinomas in theendometrium, composed of cells with granular eosinophilic or amphophilic cytoplasm, giving it a ground glassappearance. Till date, only 14 cases of this carcinoma have been reported. In this report, we have described a caseof EGCC to help define standard diagnostic criteria and better understand the course, ideal treatment, and accurateprognosis of this disease. We report a case of a 64-year-old woman diagnosed with EGCC after an abnormal papsmear. She underwent a hysteroscopy, which led to the histological diagnosis. Laparotomic total hysterectomy andbilateral salpingo-oophorectomy were performed with pelvic lymphadenectomy and peritoneal and omental biopsies. Final pathological examination confirmed the initial diagnosis. Pelvic nodes removed during surgery and peritonealand omental biopsies were negative for tumor cells. Treatment was considered appropriate and the patient did notrequire additional therapies. She was subsequently assigned to clinical follow-up and is alive, with no evidence of thedisease.