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        Cytomegalovirus Infection among Pregnant Women in Beijing: Seroepidemiological Survey and Intrauterine Transmissions

        ( Qing`e Jin ),( Jianrong Su ),( Shanna Wu ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.5

        Primary cytomegalovirus (CMV) infection during pregnancy can cause congenital defects. Available data for CMV infection during pregnancy in north China are inadequate. The aim of this study was to evaluate the epidemiology of maternal CMV infection and explore the incidence of congenital infection. In this prospective study, serum CMV IgG and IgM antibodies were measured in 2,887 pregnant women using ELISA, and the IgG avidity test was performed on all IgM-positive subjects. The seroprevalence of anti-CMV IgG was 94.70%, and of anti-CMV IgM was 1.28%. CMV IgG prevalence increased significantly with age (p < 0.01). Women living in downtown areas showed higher IgG prevalence than those residing in urban areas (p = 0.023). CMV-IgM seroprevalence was highest in autumn (p = 0.021). There was no difference in IgM seroprevalence by age, socioeconomic status, geographical area, or gravida. The rate of primary CMV infection was 0.45% (13/2,887) at the first trimester. The seroconversion rate during pregnancy was 0.76% (22/2,887). One woman underwent seroconversion during pregnancy and gave birth to an infant with asymptomatic CMV infection. Congenital CMV infection was diagnosed in five of the 14 infants from 14 mothers with active infection, for a vertical transmission rate of 35.71% (5/14). Three infants were asymptomatic, whereas two infants presented symptomatic infection with hearing deficits. Although CMV IgG prevalence is relatively high in north China, significant attention to primary CMV infection during pregnancy is still needed.

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        Synthesis and Properties of Cellulose-based Superabsorbent Hydrogel by a New Crosslinker

        Heng-Xiang Li,Xin Tian,Luming Zhang,Leili Wang,Li’e Jin,Qing Cao 한국섬유공학회 2020 Fibers and polymers Vol.21 No.7

        Cellulose-based superabsorbent hydrogel (SAH) has been successfully prepared by the grafting method withcellulose and sodium acrylate as well as aluminum hydroxide as a novel crosslinker. The factors influencing water absorptionsuch as the neutralization degree of acrylic acid (AA), the amount of initiator ammonium persulfate (APS) and crosslinker,and the proportion of cellulose to AA were investigated. The chemical structure and thermal behavior of the SAH wereanalyzed by fourier-transform infrared spectrometry, field-emission scanning electron microscopy, and thermal gravimetry,respectively. Results showed that the water absorbency of the SAH in distilled water and 0.9 wt% NaCl solution reached 922and 118 g/g when the mass ratio of cellulose to AA, APS to AA, Al(OH)3 to AA, and the neutralization degree of AA was39 wt%, 0.67 wt%, 0.89 %, and 76 %, respectively. Under the same condition, the hydrogel synthesized by traditionalcrosslinker N,N-methylenebisacrylamide was only 530 and 84 g/g in distilled water and 0.9 wt% NaCl solution, respectively. The mechanism of polymerization reaction was analyzed. And the cost and feasibility for the mass-producing the hydrogelwere analyzed.

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