RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 무료
      • 기관 내 무료
      • 유료
      • Poster Session : PS 0411 ; Infectious Disease ; High Prevalence of Hepatitis B Virus Infection Among Indonesian Migrant Workers from Lombok Island, Indonesia and Their Complete Genome Analysis

        ( Maria Inge Lusida ),( Takako Utsumi ),( Mochamad Amin ),( Juniastuti ),( Eva Triani ),( Soetjipto ),( Nasronudin ),( Yoshihiko Yano ),( Hak Hotta ),( Yoshitake Hayashi ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Due to the high endemicity of hepatitis B in Lombok population, it is important to determine its prevalence among migrant workers (MWs), since Lombok contributes the most from Indonesia abroad. Hepatitis B virus (HBV) (sub)genotypes have geographic specifi c distribution. We have reported HBV strains from Indonesian MWs based on part of envelope region and several strains could not clearly be determined their subgenotypes. In this study we analyse the whole genome sequences of those strains. Methods: Sera were collected from Indonesian MWs, to be screened for HBsAg by Enzyme Immunoassay. Those with HBsAg positive were continued with HBV DNA detection and (sub)genotype/subtype determination based on envelope region and, for several strains, on whole genome sequences. Results: Seventeen point two percent (15/87) sera from the MWs who will go to their destination countries and 12.2% (15/124) of those come back to Indonesia were HBsAg positive. All of 30 HBsAg positive samples showed hepatitis B viremia by part of envelope gene amplifi cation. Six of HBV-B genotype and one HBV-C strains were whole genome sequenced. All together showed that the most isolates (96.2%, 25/26) belonged to HBV B3/adw2 and 3.8% was HBV C8/adrq+. The whole genome phylogenetic analysis of our strains supports a recent argument that subgenotypes B5, B7, B8, B9 could be considered as a quasi-subgenotype of B3, which is most commonly found in West Indonesia, including in Lombok. Conclusions: High prevalent of HBsAg carriers in the Indonesian MWs from Lombok were found, with the predominant of HBV B3/adw2. A tight screening of HBV to the MWs should be applied, in order to limit its transmission abroad. This study also confi rmed a recent fi nding that HBV-B subgenotypes need to be reclassifi ed.

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼