http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
( Dong Hyuk Eun ),( Seok Min Kim ),( Min Ji Kim ),( Jun Young Kim ),( Yong Hyun Jang ),( Weon Ju Lee ),( Do Won Kim ),( Seok-jong Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
In-transit metastasis of malignant melanoma is a unique pattern of recurrence that occurs in up to 10 percent of patients with melanoma. Among various modalities, topical DPCP has shown meaningful but limited results in in-transit metastasis. Recently, a case treated with IL-2 intralesional injection was reported with good result. A 68-year-old man visited our clinic with recalcitrant eroded patch on Rt hallux for 2 years confirmed as malignant melanoma. Thereafter amputation of Rt hallux with ipsilateral inguinal sentinel node biopsy was done with no regional metastasis (pSTAGE IIC (T4bN0M0)). After 7 months later, complete Rt inguinal node dissection due to nodal metastasis was performed. Six-month later, multiple papulonodules were appeared on Rt groin and calf and were diagnosed as in-transit metastasis and then topical DPCP was started. After 3 months of DPCP treatment, lesion was remarkably improved, but a few months later, recurrence was confirmed by punch biopsy on Rt knee, ingenol mebutate 0.05% in addition to topical DPCP was started together. But there was no improvement for 1.5 months. Then, IL-2 intralesional injection was started together with topical DPCP. After 11 times of IL-2 with topical DPCP once a week, there were no tumor cells on surgical specimen. We report an educational case to highlight the treatment effect of IL-2 intralesional injection and topical DPCP on in-transit metastasis of malignant melanoma.
( Kyung-nam Bae ),( Kihyuk Shin ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Gun-wook Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ),( Hoon-soo Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Nodular fasciitis (NF) is a rare benign fibrous tumor related with a proliferative reactive process arising mostly from the muscular fascia or deep subcutaneous region. It distinctively appeared as solitary nodule in young-aged patient with rapid growth, which gives its other name as pseudosarcomatous fibromatosis. A 16-year old boy visited our clinic for the palpable mass on the left shoulder. The initial lesion had already been partially removed by the skin biopsy at local clinic. The biopsy specimen showed only fragments of fibrous mass consisting of collagenous stroma with spindle-shaped cells, but no atypia or mitotic figure. Surgical excision was performed, of which the surgical specimen showed invasion of spindle shaped cells involving subcutaneous layer interlacing with conspicious collagenous fiborus stroma without malignant features. After 3 months, two nodules reappeared near the operation sites and the following biopsy results showed the same as before. We decided to observe the remaining lesions and there had been no significant changes for 5 months. Multiple lesional occurrence is as quite uncommon feature of NF as the recurrence after surgical treatment. Herein, we report a rare case of multiple recurrence of NF after surgical extirpation, which presented with in-transit metastasis of sarcoma-like feature.