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      • KCI등재

        유방의 섬유낭성 변화 : 단순유방촬영상 유방실질유형과 섬유선종의 연관성

        이기열 대한영상의학회 1996 대한영상의학회지 Vol.35 No.4

        Purpose : To determine the relationship between fibrocystic change and parenchymal pattern and fibroadenoma onmammogram. Materials and Methods : Mammograms of 135 patients with histologically- diagnosed fibrocystic diseaseafter excisional biopsy were retrospectively analyzed and correlated with pathologic specimens. Classification ofthe parenchymal pattern was based on Wolfe's method. Results : On mammogram, we observed abnormality in 88 out ofthe 135 cases ; these latter consisted of 70 cases of DY, 30 of P2, 20 of P1, and 15 of Nl, following Wolfe'sparenchymal patterns. Among the 88 abnormal cases we observed 37 cases of mass with clear boundaries, five casesof mass with unclear boundaries, 22 with clustered microcalcifications, six with macrocalcifications and 18 withasymmetric dense breast. Histologic examination revealed a varying composition of stromal fibrosis, epithelialhyperplasia, cyst formation, apocrine metaplasia, etc. Histologically fibroadenomatoid change in 18 cases wasappeared as a radiopaque mass on mammogram, especially in those cases where the change was well-defined, whichwere all except three. Conclusion : Fibrocystic disease was prevalent in Wolfe's P2 and DY patterns(about 80 %).About 40 % of fibrocystic change appearing as a well defined mass on mammogram showed fibroadenomatoid changehistologically and was difficult to differentiate from fibroadenoma. Fibrocystic disease should therefore beincluded in the differential diagnosis of a mass which on mammogram is well-defined.

      • 호르몬 보충요법을 시행한 폐경여성에서 유방촬영 소견의 변화

        김양수 중앙대학교 의과대학 의과학연구소 1997 中央醫大誌 Vol.22 No.1

        I retrospectively analyzed the incidence and patterns of breast parenchymal changes of 133 follow-up mammograms in 115 postmenopausal women with hormone replacement therapy. And I also evaluated the correlations between the possible influencing factors to the mammographic changes(age, menopausal period, parenchymal pattern and duration of therapy) and incidence of parenchymal changes. Hormone replacement therapy was performed by cyclic sequntial therapy with estradiol valerate and norgestrel. The mean interval of follow-up studies was 13.7(±4.9) months. The incidence of increase in parenchymal density after hormone replacement therapy was 27%(36/133). The patterns of increased parenchymal density were focal(22%) and diffuse(78%). None of them showed decrease in parenchymal density on the follow-up mammogram. There was no statistically significant correlation between the possible influencing factors and incidence of increase in breast parenchymal density, but the duration of therapy which showed differential tendency(p=0.07). In summary, 27% of 103 follow-up mammograms in 115 postmenopausal women with hormone replacement therapy showed increased breast parenchymal density. Therefore, careful consideration is needed in interpretation of follow-up mammogram in patients with hormone replacement therapy.

      • KCI등재후보

        실리콘을 주사하여 유방확대술을 시행한 환자에서 실리콘종의 자기공명영상 소견

        한기태,김진환,한부경,최연현,Han, Ki-Tae,Kim, Jin-Hwan,Han, Boo-Kyong,Choe, Yeon-Hyeon 대한영상의학회 2002 대한영상의학회지 Vol.46 No.1

        목적: 유방확대술을 목적으로 유방내로 실리콘을 직접 주입한 후 발생한 실리콘종의 자기공명 영상소견과 그 유용성을 알아보고자 하였다. 대상과 방법: 유방확대술을 목적으로 실리콘을 유방내로 직접 주입한 환자들 중 촉지되는 종괴를 주소로 내원한 9명(18유방)을 대상으로 하여 시상,축상 자기공명영상을 시행하였다. 실리콘 종의 크기, 모양, 경계, 신호강도, 조영증강여부, 분포, 주위유방실질의 변형여부 등에 대해 조사하였으며, 실험적으로 돼지고기에 실리콘, 파라핀, 물을 넣고 자기공명영상을 얻어 각각의 신호강도차이를 알아보았다. 결과: 자기공명영상에서 실리콘종은 경계가 잘 그려지는 결절로 T1강조영상에서 저신호강도, T2강조영상에서 고신호강도로 보였으며, 조영증강 후에는 뚜렷한 조영증강을 보이지 않았다. 유방암을 가지고 있던 1명의 환자에서 종양은 비균질한 신호강도를 보이며, 조영증강이 되는 소견을 보여 자기공명영상으로 실리콘종과 뚜렷하게 구분 되었다. 돼지고기에 실리콘, 파라핀, 물을 넣고 얻은 자기공명영상에서 파라핀은 모든 펄스대열에서 매우낮은 신호강도를 보였고, 실리콘은 T1 및 지방억제 T1강조영상에서 저신호강도, T2 물억제 T2강조영상에서 고신호강도를 보였다. 결론: 유방내 실리콘을 직접 주사하여 확대술을 받은 환자에서 자기공명영상은 실리콘종과 지방조직, 유선조직 그리고 다른 병변과의 구분을 잘 하므로, 이러한 환자에서 유방내 병변을 진단하는데 유용할 것으로 생각된다. Purpose: To assess the MR findings of siliconomas (silicone granulomas) in patients with interstitial silicone injection mammoplasty. Materials and Methods: Women with interstitial silicone injection mammoplasty were referred for this study on the basis of clinical findings of palpable mass. Nine patients with 18 augmentated breasts underwent axial and sagittal MR imaging, and the results were analysed in terms of their size, shape, margin, signal intensity, enhancement pattern, distribution and adjacent parenchymal distortion. We undertook in-vitro MR imaging of silicone, paraffin, fat, and water, and then compared their signal intensities at each sequence. Results: Siliconomas were seen as well-defined low-signal-intensity nodules at T1WI and high-signal-intensity nodules at T2WI. There was no demonstrable contrast enhancement. Where there was breast cancer in which heterogeneous signal intensity was observed at T1 -and T2WI, together with heterogeneous enhancement, siliconomas were well differentiated from the tumor mass. At in-vitro MR imaging of silicone, paraffin, fat and water, paraffin showed a very low signal intensitiy at all pulse sequences but silicone showed low signal intensity at T1-fat-suppressed T1WI and high signal intensity at T2-and water-suppressed T2WI. Conclusion: MRI allows clear differentiation of siliconoma from fat and fibroglandular tissue, and can therefore, reveal anatomical details and detect lesions in patients with interstitial silicone injection mammoplasty.

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