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- 저자 : Zilong Xiang (검색결과 2 건)
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Jinyong Zhang,Muchun He,Zilong Xiang,Shufang Liu,ZhiMeng Zhuang 한국유전학회 2019 Genes & Genomics Vol.41 No.6
Background The subpeduncle lobe/olfactory lobe–optic gland axis is called the endocrine regulation center of cephalopods. However, little is known about the mechanism of the subpeduncle lobe/olfactory lobe-optic gland axis regulate the sexual maturation and post-reproductive death of Sepia esculenta Hoyle. Objectives The primary objective of this study was to provide basic information for revealing the mechanism of the subpeduncle lobe/olfactory lobe–optic axis regulating the rapid post-reproductive death of S. esculenta. Methods In this paper, Illumina sequencing based transcriptome analysis was performed on the brain tissue of female S. esculenta in the three key developmental stages: growth stage (BG), spawning stage (BS), and post-reproductive death stage (BA). Results A total of 66.19 Gb Illumina sequencing data were obtained. A comparative analysis of the three stages showed 2609, 3333, and 170 differentially expressed genes (DEGs) in BG-vs-BA, BG-vs-BA, and BS-vs-BA, respectively. The Gene Ontology (GO) enrichment analysis of DEGs revealed that the regulation of cyclin-dependent protein serine/threonine kinase activity, oxidative phosphorylation, and respiratory chain were significantly enriched. The significant enrichment analysis of the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway identified pathways associated with the regulation of death, such as the mammalian target of rapamycin (mTOR) signaling pathway, AMPK signaling pathway, oxidative phosphorylation, and cell cycle. Conclusion The post-reproductive death of S. esculenta was found to be a complex energy steady-state regulation network system. The mTOR acted as an energy receptor and had a key role in regulating energy homeostasis.
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Experimental study on bearing capacity of PFCC column-RC beam joint reinforced with CST
Ping Wu,Dongang Li,Feng Yu,Yuan Fang,Guosheng Xiang,Zilong Li 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.47 No.1
An experimental study of eleven PVC-FRP Confined Concrete (PFCC) column-Reinforced Concrete (RC) beam joints reinforced with Core Steel Tube (CST) under axial compression is carried out. All specimens are designed in accordance with the principle of “weak column and strong joint”. The influences of FRP strips spacing, length and steel ratio of CST, height and stirrup ratio of joint on mechanical behavior are investigated. As the design anticipated, all specimens are destroyed by column failure. The failure mode of PFCC column-RC beam joint reinforced with CST is the yielding of longitudinal steel bars, CST and stirrups of column as well as the fracture of FRP strips and PVC tube. The ultimate bearing capacity decreases as FRP strips spacing or joint height increases. The effects of other three studied parameters on ultimate bearing capacity are not obvious. The strain development rules of longitudinal steel bars, PVC tube, FRP strips, column stirrups and CST are revealed. The effects of various studied parameters on stiffness are also examined. Additionally, an influence coefficient of joint height is introduced based on the regression analysis of test data, a theoretical formula for predicting bearing capacity is proposed and it agrees well with test data.
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