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        Treatment of Collapsible Soils by Additions of Granulated Slag and Natural Pozzolan

        Hocine Ziani,Khelifa Abbèche,Ibrahim Messaoudene,L. J. Andrade Pais 대한토목학회 2019 KSCE Journal of Civil Engineering Vol.23 No.3

        The study of collapsible soils, due to flooding, is a major problem in soil mechanics. The majority of researches carried out regarding this type of soil have been devoted to their identification, collapse mechanisms and treatments using salts, hydraulic binders and glass fibers. However, little research has been reported on their improvements using industrial waste (e.g., slag) or natural materials (e.g., pozzolan) in order to meet environmental and socio-economic challenges. In this work, a series of tests were conducted to examine the effect of adding granulated slag and natural pozzolan, at different contents, on the suction and the collapse potential (Cp) of a soil reconstituted in the laboratory, and having a behavior similar to natural and undisturbed soils. The obtained results showed clearly that treated collapsible soils with granulated slag and natural pozzolan, lead to a significant reduction in the collapse potential (Cp) followed by a decrease of suction. Furthermore, SEM/EDAX analysis conducted on the same samples revealed that the soil pores were filled with these two materials particles and as a result a significant improvement of the physical andmechanical characteristics of the soil was noted.

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        Potential Candidates for Biomarkers in Bipolar Disorder: A Proteomic Approach through Systems Biology

        Paola Rampelotto Ziani,Jacson Gabriel Feiten,Jé,ferson Ferraz Goularte,Rafael Colombo,Bá,rbara Antqueviezc,Luiza Paul Gé,a,Adriane Ribeiro Rosa 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.2

        Bipolar disorder (BD) is one of the most disabling diseases characterized by severe humor fluctuation. It is accompanied by cognitive and functional impairment in addiction to high suicide rates. BD is often underdiagnosed and treated incorrectly because many of the reported symptoms are not exclusive to the disorder. Once the diagnosis is exclusively clinical, it is not possible to state precisely. From that, proteomic approaches were used to identify, in a large scale, all proteins involved in cellular or tissue processes. This review aggregate data from blood proteomes, by using protein association network, of subjects with BD and healthy controls to suggest dysfunctional molecular pathways involved in disease. Original articles containing proteomic analysis were searched in PubMed. Seven studies were selected and data were extracted for posterior analysis. A protein-protein interaction network was created by STRING database. A final set of proteins in this network were employed as input in ClueGO and, the main biological process was visualized using R package pathview. The analysis revealed proteins associated with many biological processes, including growth and endocrine regulation, iron transportation, protease inhibition, protection against pathogens and cholesterol transport. Moreover, pathway analysis indicated the association of uncovered proteins with two main metabolic pathways: complement system and coagulation cascade. Thus, a better understanding on the pathophysiology of psychiatric disorders and the identification of potential biomarker candidates are essential to improve diagnostic, prognostic and design pharmacological strategies.

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        NTP-ERSN verification with C5G7 1D extension benchmark and GUI development

        Lahdour, M.,El Bardouni, T.,El Hajjaji, O.,Chakir, E.,Mohammed, M.,Al Zain, Jamal,Ziani, H. Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.4

        NTP-ERSN is a package developed for solving the multigroup form of the discrete ordinates, characteristics and collision probability of the Boltzmann transport equation in one-dimensional cartesian geometry, by combining pin cells. In this work, C5G7 MOX benchmark is used to verify the accuracy and efficiency of NTP-ERSN package, by treating reactor core problems without spatial homogenization. This benchmark requires solutions in the form of normalized pin powers as well as the vectors and the eigenvalue. All NTP-ERSN simulations are carried out with appropriate spatial and angular approximations. A good agreement between NTP-ERSN results with those obtained with OpenMC calculation code for seven energy groups. In addition, our studies about angular and mesh refinements are carried out to produce better quality solution. Moreover, NTP-ERSN GUI has also been updated and adapted to python 3 programming language.

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