Preparation of polyethylenimine crosslinked chitin and its application for Reactive Black 5 removal from aqueous solutions

Zhuo Wang,GyeongMinKim,SuBinKang,SungWookWon 대한환경공학회 2018 대한환경공학회 학술발표논문집 Vol.2018 No.11

Structure-Preserving Mesh Simplification

( Zhuo Chen ),( Xiaobin Zheng ),( Tao Guan ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.11

Mesh model generated from 3D reconstruction usually comes with lots of noise, which challenges the performance and robustness of mesh simplification approaches. To overcome this problem, we present a novel method for mesh simplification which could preserve structure and improve the accuracy. Our algorithm considers both the planar structures and linear features. In the preprocessing step, it automatically detects a set of planar structures through an iterative diffusion approach based on Region Seed Growing algorithm; then robust linear features of the mesh model are extracted by exploiting image information and planar structures jointly; finally we simplify the mesh model with plane constraint QEM and linear feature preserving strategies. The proposed method can overcome the known problem that current simplification methods usually degrade the structural characteristics, especially when the decimation is extreme. Our experimental results demonstrate that the proposed method, compared to other simplification algorithms, can effectively improve the quality of mesh and yield an increased robustness on noisy input mesh.

Identifying Differentially Expressed Genes and Screening Small Molecule Drugs for Lapatinib-resistance of Breast Cancer by a Bioinformatics Strategy

Zhuo, Wen-Lei,Zhang, Liang,Xie, Qi-Chao,Zhu, Bo,Chen, Zheng-Tang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

Background: Lapatinib, a dual tyrosine kinase inhibitor that interrupts the epidermal growth factor receptor (EGFR) and HER2/neu pathways, has been indicated to have significant efficacy in treating HER2-positive breast cancer. However, acquired drug resistance has become a very serious clinical problem that hampers the use of this agent. In this study, we aimed to screen small molecule drugs that might reverse lapatinib-resistance of breast cancer by exploring differentially expressed genes (DEGs) via a bioinformatics method. Materials and Methods: We downloaded the gene expression profile of BT474-J4 (acquired lapatinib-resistant) and BT474 (lapatinib-sensitive) cell lines from the Gene Expression Omnibus (GEO) database and selected differentially expressed genes (DEGs) using dChip software. Then, gene ontology and pathway enrichment analyses were performed with the DAVID database. Finally, a connectivity map was utilized for predicting potential chemicals that reverse lapatinib-resistance. Results: A total of 1, 657 DEGs were obtained. These DEGs were enriched in 10 pathways, including cell cycling, regulation of actin cytoskeleton and focal adhesion associate examples. In addition, several small molecules were screened as the potential therapeutic agents capable of overcoming lapatinib-resistance. Conclusions: The results of our analysis provided a novel strategy for investigating the mechanism of lapatinib-resistance and identifying potential small molecule drugs for breast cancer treatment.

Size-dependent fracture properties of cracked silicon nanofilms

Zhuo, X.R.,Beom, H.G. Elsevier 2015 Materials science & engineering. properties, micro Vol.636 No.-

<P><B>Abstract</B></P> <P>We evaluate the applicability of the critical energy release rate as a crack propagation criterion with a focus on the effect of the material size. Cracked silicon nanofilms of various thicknesses under uniaxial tensile loading are simulated to examine the influence of film thickness on the critical energy release rate. Tensile stress–strain curves in addition to the atomic configurations corresponding to different strain levels are presented to elucidate the deformation mechanism. The cracked silicon nanofilms subjected to mode I loading deform nonlinearly to some extent. The critical energy release rates are calculated by three approaches: a molecular statics simulation, the Griffith criterion, and linear elastic fracture mechanics. Results obtained from these three methods are compared with each other and the differences between them are discussed. The critical energy release rate may be capable of predicting crack propagation when the silicon nanofilms are thicker than approximately 18nm.</P>

An Unconventional Outer-to-Inner Synthesis Strategy for Core (Au)-Shell Nanostructures with Photoelectrochemical Enhancement

Zhuo Zhang,Chen Bin,용기중 한국진공학회 2018 한국진공학회 학술발표회초록집 Vol.2018 No.2

Phenolic content, antioxidant capacity, and α-amylase and α-glucosidase inhibitory activities of Dimocarpus longan Lour.

Zhuo Wang,Xiaoxv Gao,Wenfeng Li,Si Tan,Qiaoran Zheng 한국식품과학회 2020 Food Science and Biotechnology Vol.29 No.5

The aim of this study was to compare the phenoliccompound profiles and antioxidant capacities of eightvarieties of longan (Dimocarpus longan Lour.) planted inthe middle and upper Yangtze River area. The totalpolyphenols content (TPC) and total flavonoids content(TFC) of dried longan pulp ranged from 1.07 ± 0.05 to1.22 ± 0.05 mg gallic acid equivalents/g and 0.25 ± 0.07to 0.87 ± 0.14 mg rutin equivalents/g. UHPLC-QqQ-MS/MS analysis revealed 12 individual polyphenol compoundsin longan. The Fuwan8, Dongliang and FD97 varietiesshowed the strongest DPPH scavenging activity (IC50 of1.03 g/mL). The highest ABTS? scavenging activity wasfound in the Dongliang. In the enzyme assays, the Fuwan8and Dongliang varieties demonstrated maximum a-amylaseand a-glucosidase inhibition activities, with values of97.56 and 88.58%, respectively. The principal componentanalysis indicated that the Rongyu8 and Songfengbencultivars have nearly analogous polyphenol compounds.

Size-dependent torsional deformation of silicon nanowires

Zhuo, Xiao Ru,Beom, Hyeon Gyu Elsevier 2018 Materials letters Vol.213 No.-

<P><B>Abstract</B></P> <P>The effect of size on the torsional deformation of [1 1 0]-oriented silicon nanowires is examined via molecular dynamics simulations. The plastic deformation mechanism of silicon nanowires depends on the nanowire diameter. Sub-5.7-nm-diameter silicon nanowires yield by means of a crystal-to-amorphous transition, which nucleates at the outer surface and propagates along the cross-section of the wires. On the other hand, perfect dislocations nucleate at the outer surface of wires whose diameter equals or exceeds 7.7 nm, initiating plastic deformation. These dislocations have a Burgers vector of 1/2 ⟨1 1 0⟩ and slip along the {1 1 1} planes. These findings may enhance our understanding of plasticity of silicon nanowires.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Torsional deformation of [1 1 0]-oriented silicon nanowires is size-dependent. </LI> <LI> Sub-5.7-nm-diameter silicon nanowires yield by a crystal-to-amorphous transition. </LI> <LI> Coaxial dislocations form in nanowires whose diameter equals or exceeds 7.7 nm. </LI> </UL> </P>

The Navigated Oblique Lumbar Interbody Fusion: Accuracy Rate, Effect on Surgical Time, and Complications

Zhuo Xi,Dean Chou,Praveen V. Mummaneni,Shane Burch 대한척추신경외과학회 2020 Neurospine Vol.17 No.1

Objective: The oblique lumbar interbody fusion (OLIF) can be done with either fluoroscopy or navigation. However, it is unclear how navigation affects the overall flow of the procedure. We wished to report on the accuracy of this technique using navigation and on how navigation affects surgical time and complications. Methods: A retrospective review was undertaken to evaluate patients who underwent OLIF using spinal navigation at University of California San Francisco. Data collected were demographic variables, perioperative variables, and radiographic images. Postoperative lateral radiographs were analyzed for accuracy of cage placement. The disc space was divided into 4 quadrants from anterior to posterior, zone 1 being anterior, and zone 4 being posterior. The accuracy of cage placement was assessed by placement. Results: There were 214 patients who met the inclusion criteria. A total of 350 levels were instrumented from L1 to L5 using navigation. The mean follow-up time was 17.42 months. The mean surgical time was 211 minutes, and the average surgical time per level was 129.01 minutes. After radiographic analysis, 94.86% of cages were placed within quartiles 1 to 3. One patient (0.47%) underwent revision surgery because of suboptimal cage placement. For approach-related complications, transient neurological symptoms were 10.28%, there was no vascular injury. Conclusion: The use of navigation to perform OLIF from L1 to L5 resulted in a cage placement accuracy rate of 94.86% in 214 patients.

Atomistic study of the bending properties of silicon nanowires

Zhuo, X.R.,Beom, H.G. Elsevier 2018 Computational materials science Vol.152 No.-

<P><B>Abstract</B></P> <P>Molecular dynamics simulations are conducted to investigate the mechanical properties and deformation mechanism of silicon nanowires (SiNWs) under pure bending, with a focus on the effects of nanowire diameter, orientation, and cross-sectional shape. The results show that the nanowire diameter and cross-sectional shape do not influence the yield mechanism but the orientation does. In contrast to [1 0 0] and [1 1 0] SiNWs whose yield mechanism is dislocation nucleation, [1 1 1] SiNWs yield by a direct crystal-to-amorphous transition. Moreover, the activated slip plane for [1 0 0] and [1 1 0] SiNWs is different, i.e., {1 1 0} and {1 1 1} plane for [1 0 0] and [1 1 0] SiNWs, respectively. The Young’s modulus of [1 0 0] and [1 1 1] SiNWs is dependent on the nanowire diameter and cross-sectional shape, whereas that of [1 1 0] SiNWs is insensitive to these factors. Furthermore, only the nanowire orientation and cross-sectional shape influence the critical bending strain of [1 0 0] and [1 1 1] SiNWs. The results presented in this work may provide valuable information for the design of nano-devices based on SiNWs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The yield mechanism of silicon nanowires depends on nanowire orientation. </LI> <LI> [1 1 1] silicon nanowires yield by a crystal-to-amorphous transition under bending. </LI> <LI> Effects of several factors on Young’s modulus are investigated. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Atomistic investigation of crack growth resistance in a single-crystal Al-nanoplate

Zhuo, Xiao Ru,Kim, Jang Hyun,Beom, Hyeon Gyu Cambridge University Press (Materials Research Soc 2016 Journal of materials research Vol.31 No.9

<▼1><B>Abstract</B><P/></▼1><▼2><P>The fracture behavior of a single-crystal Al-nanoplate with an edge crack under tensile loading was simulated using a molecular statics technique to evaluate crack growth resistance in Al. The crack length was determined using a stiffness method. A parabolic function fitted from simulation results was used to predict the crack length from the stiffness value extracted from unloading curves. Based on energy considerations, crack growth resistance was calculated. Crack growth resistance rose sharply in the initial stages of crack growth, and with an additional crack extension, it increased gradually to converge to a constant far exceeding the fracture toughness predicted by the Griffith criterion. This trend in the crack growth resistance curve was closely related to the amorphous zone formed at the crack tip after the onset of crack propagation.</P></▼2>