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      • KCI등재

        SOC ESTIMATION OF Li-ION BATTERY BASED ON IMPROVED EKF ALGORITHM

        Zhengjun Huang,Yongshou Fang,Jianjun Xu 한국자동차공학회 2021 International journal of automotive technology Vol.22 No.2

        The state of charge (SOC) is one of the important performance indicators of battery, which provides an important basis for the management and control of Battery Management System (BMS). In view of the characteristics of lithium iron phosphate battery, considering the model accuracy and calculation amount, the equivalent circuit model of improved PNGV was selected. Based on that, an improved Extended Kalman Filter (EKF) algorithm was adopted to estimate the state of charge (SOC) of Li-ion battery, which covariance matrix was modified by the Levenberg-Marquardt method. At the end of this paper, the SOC estimation algorithm was verified by MATLAB simulations. The results show that compared with the standard EKF, the improved EKF has higher estimation accuracy and anti-interference ability, and has better convergence in the estimation process.

      • KCI등재

        Simple and Green Synthesis of Boron-, Sulfur-, and Nitrogen-Co-Doped Carbon Dots as Fluorescent Probe for Selective and Sensitive Detection of Sunset Yellow

        Ying Huang,Zhengjun Cheng 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.10

        Herein, we have reported the synthesis of boron-, sulfur-, and nitrogen-co-doped carbon dots (B/S/ N-CDs) by one-step hydrothermal method using D-(+)-maltose monohydrate, boracic acid, and thiocarbamide as the precursors. The prepared B/S/N-CDs possess good water dispersibility, excellent pH stabilities, and resistance to photobleaching. Furthermore, the transmission electron microscope image indicates that the B/S/N-CDs are homogeneously spherical and show good dispersion. Noticeably, the B/S/N-CDs show bright blue photoluminescence with a quantum yield of 8.9% in aqueous solution and can be used as a potent photoluminescent probe for selective and sensitive detection of sunset yellow (SY). Compared with other food colors, SY can dramatically quench the fluorescence of B/S/N-CDs. Meanwhile, the fluorescence intensity displays a good linear response with SY concentration in the range of 0–70 μM (R2 = 0.9980) and the detection limit is as low as 4.65 nM. The B/S/N-CDs can also be applied for the detection of SY in mineral water and business drink with satisfactory recovery. Our study has demonstrated that the B/S/N-CDs may have wide application values inmedical detection, environmental monitoring, and related researches.

      • KCI등재

        Starter Culture Design to Overcome Phage Infection During Yogurt Fermentation

        Chengjie Ma,Zhengjun Chen,Guangyu Gong,Lifen Huang,Sha Li,Aimin Ma 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.2

        Streptococcus thermophilus phages present hazards for yogurt processing. In order to avoid adverse effects, different component yogurt starters were designed. For 2-component yogurt starters consisting of an S. thermophilus sensitive and a Lactobacillus delbrueckii ssp. bulgaricus strain, phage infection was destructive. Phages resulted in increased fermentation time, unbalanced cocci to rod ratios, decreased viscosity values, and varied sensory properties. For 3-component yogurt starters consisting of S. thermophilus sensitive, S. thermophilus insensitive, and L. bulgaricus strains, phage invasion did not result in the undesirable effects of slow acidification, decreased viscosity values, and unbalanced cocci to rod ratios. The 3- component yogurt starter stabilized fermentation and improved the practical fermentation performance in the presence of phages. Combinations of different S. thermophilus strains in the design and use of yogurt starters should be considered.

      • KCI등재

        Burn-resistant Coatings Lubricated on the Surface of Titanium Alloys

        Pingze Zhang,Jun Huang,Hongyan Wu,Qiang Miao,Zhengjun Yao,Zhong Xu,Zhiyong He 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.-

        Conventional titanium alloy may be ignited and burnt in conditions of high temperature, high air pressure, and high gas flow velocity. In the present study, burn-resistant coatings have been lubricated by using double glow plasma surface alloying technology. Alloying elements Cr, Mo, and Cu were induced into Ti6Al4V and Ti6.5Al0.3Mo1.5Zr0.25Si substrates through double glow discharged plasma processing, and Ti-Cr, Ti-Mo, and Ti-Cu burn-resistant alloy layers were formed on the surface of the Ti6Al4V and Ti6.5Al0.3Mo1.5Zr0.25Si alloys. The depth of the surface burn-resistant alloy layers could exceed 200 μm and the alloying-element component could reach 90%. Burn-resistant performance experimental results show that if the Cr component(wt%) is over 14%, the Cu component is over 12%, and the Mo component is over 10% in the alloying layers, ignition and burn of titanium alloy are effectively avoided. Conventional titanium alloy may be ignited and burnt in conditions of high temperature, high air pressure, and high gas flow velocity. In the present study, burn-resistant coatings have been lubricated by using double glow plasma surface alloying technology. Alloying elements Cr, Mo, and Cu were induced into Ti6Al4V and Ti6.5Al0.3Mo1.5Zr0.25Si substrates through double glow discharged plasma processing, and Ti-Cr, Ti-Mo, and Ti-Cu burn-resistant alloy layers were formed on the surface of the Ti6Al4V and Ti6.5Al0.3Mo1.5Zr0.25Si alloys. The depth of the surface burn-resistant alloy layers could exceed 200 μm and the alloying-element component could reach 90%. Burn-resistant performance experimental results show that if the Cr component(wt%) is over 14%, the Cu component is over 12%, and the Mo component is over 10% in the alloying layers, ignition and burn of titanium alloy are effectively avoided.

      • KCI등재

        Positively Charged and pH-sensitive Carbon Dots for Fluorescence Detection of Copper Ion

        Feng Feng,Chenfang Miao,Yalan Zhang,Zhengjun Huang,Shaohuang Weng 대한화학회 2021 Bulletin of the Korean Chemical Society Vol.42 No.2

        As an essential trace element in the human body, copper ion (Cu2+) performs an important role in many fundamental physiological processes that need a facile and effective method for the monitoring of Cu2+ in organisms. Herein, a turn-off, facile fluorescent strategy for sensing Cu2+ was proposed using positively charged carbon dots (P-CDs) as probe. The P-CDs prepared from melting strategy exhibited stable, biocompatible, and pH-sensitive luminescent properties. P-CDs can be selectively quenched by Cu2+ for the direct detection of Cu2+. The reaction mechanism between Cu2+ and P-CDs was systematically investigated, illustrating that Cu2+ coordinated with the surface functional groups in P-CDs. The binding effect of Cu2+ and P-CDs caused the constant morphology and static quenching behavior of P-CDs. The promising accuracy of the testing results of the addition of Cu2+ in diluted serum using P-CDs implied their extended application in the biological field.

      • KCI등재

        Drug-loaded microbubble delivery system to enhance PD-L1 blockade immunotherapy with remodeling immune microenvironment

        Zheng Jun,Huang Ju,Zhang Liang,Wang Mengna,Xu Lihong,Dou Xiaoyun,Leng Xiaojing,Fang Mingxiao,Sun Yang,Wang Zhigang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

        Although programmed cell death protein 1 (PD-1)/ programmed cell death-ligand protein 1 (PD-L1) checkpoint blockade immunotherapy demonstrates great promise in cancer treatment, poor infiltration of T cells resulted from tumor immunosuppressive microenvironment (TIME) and insufficient accumulation of anti-PD-L1 (αPD-L1) in tumor sites diminish the immune response. Herein, we reported a drug-loaded microbubble delivery system to overcome these obstacles and enhance PD-L1 blockade immunotherapy.Docetaxel (DTX) and imiquimod (R837)-loaded microbubbles (RD@MBs) were synthesized via a typical rotary evaporation method combined with mechanical oscillation. The targeted release of drugs was achieved by using the directional "bursting" capability of ultrasound-targeted microbubble destruction (UTMD) technology. The antitumor immune response by RD@MBs combining αPD-L1 were evaluated on 4T1 and CT26 tumor models.The dying tumor cells induced by DTX release tumor-associated antigens (TAAs), together with R837, promoted the activation, proliferation and recruitment of T cells. Besides, UTMD technology and DTX enhanced the accumulation of αPD-L1 in tumor sites. Moreover, RD@MBs remolded TIME, including the polarization of M2-phenotype tumor-associated macrophages (TAMs) to M1-phenotype, and reduction of myeloid-derived suppressor cells (MDSCs). The RD@MBs + αPD-L1 synergistic therapy not only effectively inhibited the growth of primary tumors, but also significantly inhibited the mimic distant tumors as well as lung metastases.PD-L1 blockade immunotherapy was enhanced by RD@MBs delivery system.

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