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Ping, An,Zhendong, Su,Rongmei, Qu,Jingxing, Dai,Wei, Chen,Zhongyin, Zhou,Hesheng, Luo,Soh, Kwang-Sup Hindawi Publishing Corporation 2015 Evidence-based Complementary and Alternative Medic Vol.2015 No.-
<P>Gastric cancer is the fourth commonest cancer in the world and the second leading cause of cancer-related death. Investigation of gastric cancer metastasis is one of the hottest and major focuses in cancer research. Growing evidence manifested that primo vascular system (PVS) is a new kind of circulatory system beyond vascular and lymphatic system. Previous researches revealed that PVS is a specific tissue between endothelium and mesenchyme and is involved in cancer, especially in tumor metastasis and regeneration. In current study, we investigated the role of primo vessels in gastric cancer metastasis and its possible relationship to vascular vessels formation. Our results indicated that primo vessels were involved in gastric cancer metastasis. We observed blood vessel-mediated metastasis, primo vessel-mediated metastasis, and an intermediate state between them. We deduced that primo vessels may be precursors of blood vessels. These results possibly provided a thoroughly new theoretic development in cancer metastasis.</P>
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Analysis of Toe Formation in Stress-Concentration Zones on High Rock Slopes
Ke Deng,Ming Chen,Peng Yan,Zhendong Leng,Guangdong Yang 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.2
Toe formation is a phenomenon resulting from unconnected cracks between blastholes,which occurred during blasting excavation of the abutment slot at Baihetan hydropower station. Analysis of crack development has tended not to focus on the high in-situ stress environment at the slope corner. Therefore, this study aimed to explore the toe formation process through theoretical analysis and numerical simulation. Firstly, a three-blasthole model was established to analyze the effects of blasting load and in-situ stress on crack extension. Then, a finite-element model of the abutment slot was built to simulate crack propagationunder different in-situ stress environment. Finally, optimization measures for avoiding toe were proposed. The results demonstrate that cracks grow preferentially in the direction of the maximum tangential tensile stress and are influenced by the blasting load and in-situ stress. On the lateral side of the abutment slot, the crack initiation and extension occur far from the centerline due to the deviation of the maximum tangential tensile stress. The deviation increased as the in-situ stress. Consequently, cracks between blastholes not being able to connect with each other results in toe formation. Increment of the linear density of the charge and optimization of the excavated profile are both effective in reducing the impact of the stress concentration caused by in-situ stress and preventing toe formation.
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Zhengyi Wu*,Liang Sun*,Ke Ning,Zhendong Chen,Zhipeng Wu,Hanqing Yang,Jinlong Yan*,Xiangbao Yin* 대한외과학회 2023 Annals of Surgical Treatment and Research(ASRT) Vol.105 No.6
Purpose: This study was performed to analyze the rule of confluence of the caudate lobe bile duct (CLD) into the left hepatic duct (LHD) and to discuss the protective strategy during left hemihepatectomy. Methods: MRI of 400 patients and T-tube angiography images of 100 patients were collected, and the imaging rules of the confluence of the CLD into the LHD were summarized. The clinical data of 33 patients who underwent left hemihepatectomy using the protective strategy were analyzed. Results: MRI and T-tube angiography images showed that the length from the confluence point of the CLD into the LHD to the confluence of the left and right hepatic ducts was 1.19 ± 0.40 cm and 1.26 ± 0.39 cm, respectively. The average angle between the longitudinal axis of the 2 bile ducts was 68.27° ± 22.59° and 66.58 ± 22.88°, respectively. Coronal and cross-sectional images showed that inflow from the foot side to the cranial side was noted in 79.8% and 82.0% of patients, respectively, and inflow from the dorsal to the ventral side was observed in 84.5% and 88.0%, respectively. Based on these imaging rules, the safe transection length and plane were summarized, and the CLD was effectively protected in 33 cases of left hemihepatectomy. Conclusion: In left hemihepatectomy, the LHD should be transected at least 1.5 cm away from the confluence of the left and right hepatic ducts, and the plane of transection should be oblique to the dorsal side at an angle of 45° with the LHD, these parameters represent an effective strategy to protect the CLD.
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