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RISS 인기검색어
- 검색키워드
- 저자 : Zeinab A. Salem (검색결과 3 건)
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Entesar A. Hassan,Hamada M. Mashaly,Zeinab M. Hashem,Salem E. Zayed,Ahmed M. Abo-Bakr 한국섬유공학회 2022 Fibers and polymers Vol.23 No.9
A series of varying and poly-functionalized heterocyclic compounds 3a-c, 4d-k, 6a,b, 8, 9, and 12 containing azofunction have been synthesized using 2-(1-(4-aminophenyl)ethylidene)malononitrile (1) and/or its diazonium salt as buildingblocks. In addition, new pyridazine derivatives 4a-c, 7a,b, and 13a-f were synthesized. Subsequent treating of the resultedazo dyes moieties with different reagents in conventional and green conditions using microwave irradiation and shrimp chitinas a green catalyst; homo- and hetero-molecules containing azo dyes were gathered. The obtained azo dyes were applied onfabrics at high temperatures and their properties such as washing fastness using standard soap (SDS) and rubbing fastness(wet and dry) under controlled conditions of pressure, speed, and moisture were studied. In addition, they were screened fortheir biological activities on two bacterial and two mycolic species. The synthesized products were characterized by theirelemental and spectral analyses such as IR, MS, 1H-NMR, and 13C-NMR spectra. The produced dyestuffs 3a-c, 4d, f, h, i, j,6a,b, 8, and 12 were dyed on polyester fabrics, and subsequently their dyeing properties and their light, washing, perspiration,rubbing, and sublimation fastness was determined and the dyed samples showed very good fastness levels to rubbing,washing, thermal fixation, good light, and possessed very good perspiration fastness.
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Tahany Haggag,Elham F. Mahmoud,Zeinab A. Salem,Nermeen AbuBakr 대한해부학회 2020 Anatomy & Cell Biology Vol.53 No.4
The tongue is a specialized vital organ. It aids in mastication, deglutition and food digestion. It also shares in the perception of taste sensation as it possesses various gustatory papillae. It is being subjected to numerous anatomical and histological examinations aiming at exploring the correlation between its morphological features and animal adaptations to various types of nutrition and environmental conditions. The goal of the present work was to compare the ultrastructural features of the filiform and fungiform papillae of three various mammals possessing different feeding habits; Egyptian mice, fruit bats and long-eared hedgehogs. Specimens were obtained from the tongues of four healthy adult animals from each mammalian type. Tongues were fixed and all the appropriate procedures were done to perform scanning electron microscopic investigation. Scanning electron microscopic examination demonstrated that in mice, there were four different sub-types of filiform papillae (spike, leaf, conical and tongue-shaped). In bats, there were two sub-types (flower and leaf-like) and in hedgehogs, there was only one type (tongue-like). These filiform papillae showed different distribution and orientation. As for the fungiform papillae, they were cylindrical in mice, rounded or conical in bats and dome-shaped in hedgehogs. Fungiform papillae possessed taste pores containing taste buds. Ultrastructural variations of the filiform and fungiform papillae were suggested to be probably due to adaptation to various feeding habits and different environmental conditions of these animals.
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MicroRNAs and Metastasis-related Gene Expression in Egyptian Breast Cancer Patients
Hafez, Mohamed M.,Hassan, Zeinab K.,Zekri, Abdel Rahman N.,Gaber, Ayman A.,Rejaie, Salem S. Al,Sayed-Ahmed, Mohamed M.,Shabanah, Othman Al Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Aim and background: MicroRNAs (miRNAs) are a class of naturally occurring small noncoding RNAs that regulate gene expression, cell growth, differentiation and apoptosis by targeting mRNAs for translational repression or cleavage. The present study was conducted to study miRNAs in Egyptian breast cancer (BC) and their relation to metastasis, tumor invasion and apoptosis in addition to their association with the ER and PR statuses. Methods: Real Time RT-PCR was performed to identify the miRNA expression level of eight miRNAs and eight metastatic-related genes in 40 breast cancer samples and their adjacent non-neoplastic tissues. The expression levels of each miRNA relative to U6 RNA were determined using the $^{2-{\Delta}}CT$ method. Also, miRNA expression profiles of the BC and their corresponding ANT were evaluated. Results: The BC patients showed an up-regulation in miRNAs (mir-155, mir-10, mir-21 and mir-373) with an upregulation in MMP2, MMp9 and VEGF genes. We found down regulation in mir-17p, mir-126, mir-335, mir-30b and also TIMP3, TMP1 and PDCD4 genes in the cancer tissue compared to the adjacent non-neoplastic tissues. Mir -10b, mir -21, mir-155 and mir373 and the metastatic genes MMP2, MMP9 and VEGF were significantly associated with an increase in tumor size (P < 0.05). No significant difference was observed between any of the studied miRNAs regarding lymph node metastasis. Mir-21 was significantly over-expressed in ER-/PR-cases. Conclusion: Specific miRNAs (mir-10, mir-21, mir-155, mir-373, mir-30b, mir-126, mir-17p, mir-335) are associated with tumor metastasis and other clinical characteristics for BC, facilitating identification of individuals who are at risk.
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