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RISS 인기검색어
- 검색키워드
- 저자 : Yutong Xu (검색결과 5 건)
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Zou Yutong,Wang Danchen,Cheng Xinqi,Ma Chaochao,Lin Songbai,Hu Yingying,Yu Songlin,Xia Liangyu,Li Honglei,Yin Yicong,Liu Huaicheng,Zhang Dianxi,Zhang Kui,Lian Xiaolan,Xu Tengda,Qiu Ling 대한진단검사의학회 2021 Annals of Laboratory Medicine Vol.41 No.1
Background: Thyroid diseases are highly prevalent worldwide, but their diagnosis remains a challenge. We established reference intervals (RIs) for thyroid-associated hormones and evaluated the prevalence of thyroid diseases in China. Methods: After excluding outliers based on the results of ultrasound screening, thyroid antibody tests, and the Tukey method, the medical records of 20,303 euthyroid adults, who visited the Department of Health Care at Peking Union Medical College Hospital from January 2014 to December 2018, were analyzed. Thyroid-associated hormones were measured by the Siemens Advia Centaur XP analyzer. The RIs for thyroid-associated hormones were calculated according to the CLSI C28-A3 guidelines, and were compared with the RIs provided by Siemens. The prevalence of thyroid diseases over the five years was evaluated and compared using the chi-square test. Results: The RIs for thyroid stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), total thyroxine (TT4), and total triiodothyronine (TT3) were 0.71–4.92 mIU/L, 12.2–20.1 pmol/L, 3.9–6.0 pmol/L, 65.6–135.1 nmol/L, and 1.2–2.2 nmol/L, respectively. The RIs of all hormones except TT4 differed significantly between males and females. The RIs of TSH increased with increasing age. The prevalence of overt hypothyroidism, overt hyperthyroidism, subclinical hypothyroidism, and subclinical hyperthyroidism was 0.5% and 0.8%, 0.2% and 0.6%, 3.8% and 6.1%, and 3.3% and 4.7% in males and females, respectively, which differed from those provided by Siemens. Conclusions: Sex-specific RIs were established for thyroid-associated hormones, and the prevalence of thyroid diseases was determined in the Chinese population.
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A real-time hybrid testing method for vehicle-bridge coupling systems
Guoshan Xu,Yutong Jiang,Xizhan Ning,Zhipeng Liu 국제구조공학회 2024 Smart Structures and Systems, An International Jou Vol.33 No.1
The investigation on vehicle-bridge coupling system (VBCS) is crucial in bridge design, bridge condition evaluation, and vehicle overload control. A real-time hybrid testing (RTHT) method for VBCS (RTHT-VBCS) is proposed in this paper for accurately and economically disclosing the dynamic performance of VBCSs. In the proposed method, one of the carriages is chosen as the experimental substructure loaded by servo-hydraulic actuator loading system in the laboratory, and the remaining carriages as well as the bridge structure are chosen as the numerical substructure numerically simulated in one computer. The numerical substructure and the experimental substructure are synchronized at their coupling points in terms of force equilibrium and deformation compatibility. Compared to the traditional iteration experimental method and the numerical simulation method, the proposed RTHT-VBCS method could not only obtain the dynamic response of VBCS, but also economically analyze various working conditions. Firstly, the theory of RTHT-VBCS is proposed. Secondly, numerical models of VBCS for RTHT method are presented. Finally, the feasibility and accuracy of the RTHT-VBCS are preliminarily validated by real-time hybrid simulations (RTHSs). It is shown that, the proposed RTHT-VBCS is feasible and shows great advantages over the traditional methods, and the proposed models can effectively represent the VBCS for RTHT method in terms of the force equilibrium and deformation compatibility at the coupling point. It is shown that the results of the single-degree-offreedom model and the train vehicle model are match well with the referenced results. The RTHS results preliminarily prove the effectiveness and accuracy of the proposed RTHT-VBCS.
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Antimicrobial and Cytotoxic Activity of Endophytic Fungi from Lagopsis supina
Zhang Dekui,Sun Weijian,Xu Wenjie,Ji Changbo,Zhou Yang,Sun Jingyi,Tian Yutong,Li Yanling,Zhao Fengchun,Tian Yuan 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.4
In this study, five endophytic fungi belonging to the Aspergillus and Alternaria genera were isolated from Lagopsis supina. The antimicrobial activity of all fungal fermented extracts against Staphylococcus and Fusarium graminearum was tested using the cup-plate method. Among them, Aspergillus ochraceus XZC-1 showed the best activity and was subsequently selected for large-scale fermentation and bioactivity-directed separation of the secondary metabolites. Four compounds, including 2- methoxy-6-methyl-1,4-benzoquinone (1), 3,5-dihydroxytoluene (2), oleic acid (3), and penicillic acid (4) were discovered. Here, compounds 1 and 4 displayed anti-fungal activity against F. graminearum, F. oxysporum, F. moniliforme, F. stratum, Botrytis cinerea, Magnaporthe oryzae, and Verticillium dahliae with diverse MIC values (128–512 μg/ml), which were close to that of the positive control antifungal, actidione (64–128 μg/ml). Additionally, compounds 1 and 4 also exhibited moderate antibacterial activity against S. aureus, Listeria monocytogenes, Escherichia coli, and Salmonella enterica, with low MIC values (8–64 μg/ml). Moreover, compounds 1 and 4 displayed selective cytotoxicity against cancer cell lines as compared with the normal fibroblast cells. Therefore, this study proposes that the endophytic fungi from L. supina can potentially produce bioactive molecules to be used as lead compounds in drugs or agricultural antibiotics.
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Design of an Optical System for a Space Target Detection Camera
Liu Zhang,Jiakun Zhang,Jingwen Lei,Yutong Xu,Xue-Ying Lv 한국광학회 2022 Current Optics and Photonics Vol.6 No.4
In this paper, the details and design process of an optical system for space target detection cameras are introduced. The whole system is divided into three structures. The first structure is a short-focus vis-ible light system for rough detection in a large field of view. The field of view is 2°, the effective focallength is 1,125 mm, and the F-number is 3.83. The second structure is a telephoto visible light systemfor precise detection in a small field of view. The field of view is 1°, the effective focal length is 2,300mm, and the F-number is 7.67. The third structure is an infrared light detection system. The field ofview is 2°, the effective focal length is 390 mm, and the F-number is 1.3. The visible long-focus narrowfield of view and visible short-focus wide field of view are switched through a turning mirror. Design results show that the modulation transfer functions of the three structures of the system are close to the diffraction limit. It can further be seen that the short-focus wide-field-of-view distortion is controlledwithin 0.1%, the long-focus narrow-field-of-view distortion within 0.5%, and the infrared subsystem distortion within 0.2%. The imaging effect is good and the purpose of the design is achieved.
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