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Wang Sicen,He Lang chong,Yun Sofeng The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.3
The present study was designed to study the difference effects between nicardipine and its two enantiomers on thoracic artery of rabbit. A high-performance liquid chromatographic method was used to prepare the two enantiomers of nicardipine. The thoracic artery of rabbit was removed. The vessels were cut into 3 mm in width and 15 mm in length spiral strips and immersed into tissue baths. The concentration-response curves of nicardipine and its enantiomers were obtained by cumulative administration of the vasoconstrictors. Nicardipine and the enantiomers could shift the dose-response curves of NE, KCI or CaCl$_2$ to right in a nonparallel manner and decrease the maximum effective in a concentration-depended manner, respectively. The pD$_2$' value of R-(-)-nicardipine showed significantly effective than that of nicardipine and S-(+)-nicardipine (P<0.01). There was not obviouse difference between the pD$_2$' value of nicardipine and S-(+)-nicardipine (P>0.05). The results demonstrate that the stereoselective interaction between R-(-)-nicardipine and L-calcium channel receptor is more stronger than that of S-(+)-nicardipine.
Chong Shang,Yun-Bao Ma,Yuan Wang,Xiao-Feng He,Tian-Ze Li,Ji-Jun Chen 대한약학회 2023 Archives of Pharmacal Research Vol.46 No.10
Artemongolins A–K (1–11), which are undescribed sesquiterpenoid dimers, were obtained from Artemisia mongolica and characterized through comprehensive spectral data, including HRESIMS, IR, 1D and 2D NMR, and ECD calculations. The absolute configurations of compounds 1, 4, and 7 were undoubtedly determined by a single-crystal X-ray crystallography. Artemongolins A–K (1–11) featured a rare 5/7/5/5/5/10 hexacyclic system composed of a germacrene and a guaianolide by a fused 2-oxaspiro[4,4]nonane-1-one ring system. Antihepatoma evaluation against three human hepatoma cell lines demonstrated that the most active compounds 5 and 6 displayed inhibitory activity with IC50 values of 88.6 and 57.0 (HepG2), 59.1 and 26.4 (Huh7), and 67.5 and 32.5 (SK-Hep-1) µM, respectively.
Effects of Ohmic Area Etching on Buffer Breakdown Voltage of AlGaN/GaN HEMT
Wang, Chong,Wel, Xiao-Xiao,Zhao, Meng-Di,He, Yun-Long,Zheng, Xue-Feng,Mao, Wei,Ma, Xiao-Hua,Zhang, Jin-Cheng,Hao, Yue The Korean Institute of Electrical and Electronic 2017 Transactions on Electrical and Electronic Material Vol.18 No.3
This study is on how ohmic area etching affects the buffer breakdown voltage of AlGaN/GaN HEMT. The surface morphology of the ohmic metal can be improved by whole etching on the ohmic area. The buffer breakdown voltages of the samples with whole etching on the ohmic area were improved by the suppression of the metal spikes formed under the ohmic contact regions during high-temperature annealing. The samples with selective etching on the ohmic area were investigated for comparison. In addition, the buffer leakage currents were measured on the different radii of the wafer, and the uniformity of the buffer leakage currents on the wafer were investigated by PL mapping measurement.
Effects of Ohmic Area Etching on Buffer Breakdown Voltage of AlGaN/GaN HEMT
Chong Wang,Xiao-Xiao Wel,Meng-Di Zhao,Yun-Long He,Xue-Feng Zheng,Wei Mao,Xiao-Hua Ma,Jin-Cheng Zhang,Yue Hao 한국전기전자재료학회 2017 Transactions on Electrical and Electronic Material Vol.18 No.3
This study is on how ohmic area etching affects the buffer breakdown voltage of AlGaN/GaN HEMT. The surfacemorphology of the ohmic metal can be improved by whole etching on the ohmic area. The buffer breakdown voltagesof the samples with whole etching on the ohmic area were improved by the suppression of the metal spikes formedunder the ohmic contact regions during high-temperature annealing. The samples with selective etching on theohmic area were investigated for comparison. In addition, the buffer leakage currents were measured on the differentradii of the wafer, and the uniformity of the buffer leakage currents on the wafer were investigated by PL mappingmeasurement.
Yun Long,Chong Yao,En-Zhe Song,Quan Dong,Yan-Min Wang 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.2
In this paper, an adaptive second-order sliding mode control approach is proposed for the performance improvement of electronic throttles (ET). Based on the traditional twisting approach, a novel adaptation mechanism based on the online zero-crossing checking is contained in the modified approach to make the control magnitude of the controller at the minimum admissible level. The idea behind it is to calculate the number of zero-crossings of the sliding surface in real time. The guaranteed stability condition and convergence region of the system are also deduced. In order to further prove its high adaptation capability, the commonly used adaptation mechanism called the Lyapunov-based type is also introduced for comparative study. Simulations and experiments validate the proposed approach with the advantages of chattering elimination, high speed and accuracy in the control of ET systems.
DBI 구조를 이용한 35[W] 세라믹 메탈 할라이드 램프용 전자식 안정기의 설계
박종연(Chong-Yun Park),최왕섭(Wang-Seop Choe) 한국조명·전기설비학회 2010 조명·전기설비학회논문지 Vol.24 No.9
Ceramic metal halide lamps have been widely used due to long lifetime, high luminous efficiency and good colour rendering. 35[W] ceramic metal halide lamps has very different characteristics between ignition state and steady state. The developed electronic ballast is satisfied to both ignition state and steady state characteristics by using a micro-controller. The proposed electronic ballast is consists of EMI filter, Full-wave rectifier, Active PFC, DBI(Dual Buck Inverter), Igniter and control circuit. It enables to supply both low-frequency rectangular wave voltage and current to the lamp by using DBI(Dual Bcuk Inverter) structure.
Antiferroelectric Liquid Crystal from Bent-Core Molecule with Vinyl End Group
Lee, Chong-Kwang,Kwon, Soon-Sik,Kim, Tae-Sung,Shin, Sung-Tae,Choi, Hong,Choi, E. Joon,Kim, Sea-Yun,Zin, Wang-Choel,Kim, Dae-Choel,Chien, Liang-Chy Korean Chemical Society 2004 Bulletin of the Korean Chemical Society Vol.25 No.8
Three banana-shaped achiral compounds, 4-chloro-1,3-phenylene bis [4-{4-(undecenyloxy)phenyl imino-methyl} benzoate] derivatives, were synthesized with variation of a substituent (x=H, F, Cl); their antiferro-electric properties are described. The smectic mesophases, including a switchable chiral smectic C(Sm $C^{\ast}$) phase, were characterized by differential scanning calorimetry, polarizing optical microscopy, triangular wave method, and X-ray diffractometry. The presence of vinyl groups at the terminals of linear side wings in the banana-shaped achiral molecules induced a decrease in melting temperature and formation of the switchable Sm $C^{\ast}$ phase in the melt. The smectic phase having a lateral fluorine-substituent at 3-position of the Schiff's base moiety showed antiferroelctric switching, and the value of spontaneous polarization on reversal of an applied electric field was 250 nC/$cm^2$ .
박종연(Chong-Yun Park),최왕섭(Wang-Seop Choe),이규민(Kyu-Min Lee) 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.7
Dual Buck Inverter 구조를 갖는 35W 세라믹 MHL용 전자식 안정기의 제어회로를 설계하였다. 제어회로는 크게 2가지로 나눌 수 있는데 PFC IC를 이용하여 Inverter의 전압과 전류를 센싱하여 80㎑로 Inverter를 구동하기 위한 제어부분과 시간의 경과에 따른 PFC의 출력 전압 제어, Ignition Pulse 제어 및 무부하 보호, 램프의 점등 상태에 따른 Inverter 구동 주파수 제어부분으로 구성되어 있다. 본 논문은 마이크로 컨트롤러(ATmega8)를 이용하여 시간의 경과에 따른 안정기의 제어부분에 대해 설명하고 이를 실험을 통해 검증하였다.
DBI 구조의 전자식 안정기를 이용한 70W CDM 램프용 조광제어 시스템 개발
최왕섭(Choe, Wang-Seop),유진완(Yoo, Jin-Wan),박종연(Park, Chong-Yun) 강원대학교 산업기술연구소 2011 産業技術硏究 Vol.31 No.1
Ceramic metal halide lamps have been widely used due to long lifetime, high luminous efficiency and good colour rendering. In this paper, we developed dimming control system of electronic ballast for 70W ceramic metal halide lamp by using 1-10V interface. The proposed electronic ballast is consists of EMI filter, Full-wave rectifier, Active PFC, DBI(Dual Buck Inverter), Igniter and control circuit.It enables to supply both low-frequency rectangular wave voltage and current to the lamp by using DBI(Dual Bcuk Inverter) structure. By using 1-10V interface, the system that able to dimming the lamp is demonstrated by P-spice simulation and experimental results.