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- 저자 : Yufeng Mao (검색결과 2 건)
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Lei Mao,Fei Wang,Yuanyuan Li,Yufeng Dai,Yanjun Liu,Jingfeng Wang,Changhu Xue 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.2
Glucocorticoids are the leading cause of secondaryosteoporosis. In the current study, the in vivoeffects of Antarctic krill (Euphausia superba) oil (AKO) ondexamethasone-treated mice were investigated. Resultsshowed that AKO significantly prevents bone loss, asevidenced by improved bone mineral density, biomechanicalstrength, and cancellous bone microstructure. Fluorescencedouble-labeling of femur showed that AKOinduces new bone formation. Toluidine blue staining ofmarrow cavity indicated that AKO increases the number oftrabecula, and decreases the generation of adipose cells. Runt-related transcription factor 2 (Runx2) and Peroxisomeproliferator-activated receptor c (PPARc) are the switchesfor osteogenic and adipogenic differentiation of bonemarrow mesenchymal stem cells, respectively. AKO significantlypromoted the expression of Runx2 protein, andreduced PPARc expression in bone tissue. Furthermore,AKO increased the mRNA expression of osteogenesis-relatedgenes and decreased the expression of adipogenesisrelatedgenes. In conclusion, AKO improved glucocorticoid-induced osteoporosis via promoting bone formation.
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Yue Zhang,Yufeng Mao,Zhen Wang,Chengfei Gao 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.5
A vibration isolator system with nonlinear stiffness is designed and tested to solve problems on marine noise measuring equipment which are caused by underwater flow. The low frequency response characteristics of the vibration isolation system are evaluated from static function and dynamic simulation with Harmonic Balance Method. The theoretical analysis results show that the total stiffness value of the isolator system will be kept in 0 point around when parallel springs stay in equilibrium position. In order to assess the practical efficiency of Quasi-Zero-Stiffness (QZS) isolator, a vibration response test is carried out. By comparing the acceleration signals at 5 Hz and 100 Hz between linear and nonlinear system in time domain and frequency domain, the transmissibility curves are obtained. The experimental results demonstrate that the isolation system expands the frequency range of operation effectively by decreasing the natural frequency of the QZS vibration isolator. In addition, the QZS isolation system decreases the transmissibility of vibration by reducing the amplitude of output signals. The QZS isolator has more outstanding performance in contrast to linear spring in ultralow frequency isolation field.
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