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Yu-Lin Hsieh,Hsien-Tsung Yao,Ron-Shan Cheng,Meng-Tsan Chiang 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.5
Chitosan is a natural product derived from chitin. To investigate the hypoglycemic and anti-obesity effects of chitosan, male Sprague–Dawley rats were divided into four groups: normal control, diabetic, and diabetic fed 5% or 7%chitosan. Diabetes was induced in rats by injecting streptozotocin/nicotinamide. After 10 weeks of feeding, the elevated plasma glucose, tumor necrosis factor-a, and interleukin-6 and lower adiponetin levels caused by diabetes were effectively reversed by chitosan treatment. In addition, 7% chitosan feeding also elevated plasma glucagon-like peptide-1 levels and lowered the insulin resistance index (homeostasis model assessment) in diabetic rats. Lower adipocyte granular intensities and higher lipolysis rates in adipose tissues were noted in the 7% chitosan group. Moreover, chitosan feeding reduced hepatic triglyceride and cholesterol contents and increased hepatic peroxisomal proliferator-activated receptor a expression in diabetic rats. Our results indicate that long-term administration of chitosan may reduce insulin resistance through suppression of lipid accumulation in liver and adipose tissues and amelioration of chronic inflammation in diabetic rats.
Shan Cheng,Han Dong,Li Yu,Dongmei Zhang,Jinchen Ji 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.1
This brief paper studies the consensus problem of second-order multi-agent systems when the agents’ velocitymeasurements are unavailable. Firstly, two simple consensus protocols which do not need velocity measurementsof the agents are derived to guarantee that the multi-agent systems achieve consensus in directed networks. Secondly, a key constant which is determined by the complex eigenvalue of the nonsymmetric Laplacian matrix andan explicit expression of the consensus state are respectively developed based on matrix theory. The obtained resultsshow that all the agents can reach consensus if the feedback parameter is bigger than the key constant. Thirdly,the theoretical analysis shows that the followers can track the position and velocity of the leader provided that theleader has a directed path to all other followers and the feedback parameter is bigger enough. Finally, numericalsimulations are given to illustrate the effectiveness of the proposed protocols.
Yu-Yang Chi,Jing-Lin Shen,Jing Zhang,Anshan Shan,Shu-Ling Niu,Chang-Hai Zhou,이홍구,Yong-Cheng Jin 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.4
The aim of this study is to reveal the relation among villin 2, Wnt/β-catenin, andadipogenesis by adding appropriate lithium chloride (LiCl). The study comprises three parts: theselection of LiCl concentration, the effect of LiCl on adipocyte differentiation during and afterdifferentiation induction. By comprehensively analyzing the results of the experiments, we proved thatLiCl can inhibit adipocyte differentiation and enhance villin 2 and β-catenin expressions not only duringdifferentiation induction but also after it. Moreover, villin 2 has a significant impact on β-catenin. Wesuggest that villin 2 may participate in Wnt/β-catenin signaling.
Shan Cheng,Li Yu,Dongmei Zhang,Jinchen Ji 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1
This brief paper studies the stationary consensus of multiple Euler-Lagrange systems with nonlinear protocols. Two consensus protocols are given to guarantee that positions and velocities of multiple Euler-Lagrangesystems reach consensus. Proposed protocols need only the relative position measurements and the velocity measurementsof one Euler-Lagrange system. Finally, numerical simulations are given to illustrate the theoreticalresults.
Attention Capsule Network for Aspect-Level Sentiment Classification
( Yu Deng ),( Hang Lei ),( Xiaoyu Li ),( Yiou Lin ),( Wangchi Cheng ),( Shan Yang ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.4
As a fine-grained classification problem, aspect-level sentiment classification predicts the sentiment polarity for different aspects in context. To address this issue, researchers have widely used attention mechanisms to abstract the relationship between context and aspects. Still, it is difficult to effectively obtain a more profound semantic representation, and the strong correlation between local context features and the aspect-based sentiment is rarely considered. In this paper, a hybrid attention capsule network for aspect-level sentiment classification (ABASCap) was proposed. In this model, the multi-head self-attention was improved, and a context mask mechanism based on adjustable context window was proposed, so as to effectively obtain the internal association between aspects and context. Moreover, the dynamic routing algorithm and activation function in capsule network were optimized to meet the task requirements. Finally, sufficient experiments were conducted on three benchmark datasets in different domains. Compared with other baseline models, ABASCap achieved better classification results, and outperformed the state-of-the-art methods in this task after incorporating pre-training BERT.
Lu, Yu,Bao, Jin-Gui,Deng, Yan,Rong, Cheng-Zhi,Liu, Yan-Qiong,Huang, Xiu-Li,Song, Liu-Ying,Li, Shan,Qin, Xue Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14
Background: The aim of this study was to assess the relationship between IL-18 gene polymorphisms and HBV-related diseases and whether these polymorphisms influence its expression in the Guangxi Zhuang population. Materials and Methods: We enrolled 129 chronic HBV infected (CHB) patients, 86 HBV-related liver cirrhosis (LC) patients and 160 healthy controls in our study. Polymerase chain reaction-restriction fragment length polymorphism methods were used to detect IL-18 gene -607C/A, -137G/C polymorphisms, and an ELISA kit was employed to determine serum IL-18 levels. Results: No correlation was found between the -607C/A polymorphism and risk of HBV-related disease. For the -137G/C polymorphism, the GC genotype and C allele were associated with a significantly lower risk of CHB (95%CI: 0.32-0.95, p=0.034 and 95%CI: 0.35-0.91, p=0.018) and HBV-related LC (95%CI: 0.24-0.89, p=0.022 and 95%CI: 0.28-0.90, p=0.021). A similar decreased risk was also found with the A-607C-137 haplotype. With respect to IL-18 expression, it was significantly lower in both patient groups, but no association was noted between the two polymorphisms in the IL-18 gene and its expression. Conclusions: Our study indicated that the -137C allele in the IL-18 gene may be a protective factor for HBV-related disease, and serum IL-18 level may be inversely associated with CHB and HBV-related LC.
Thruster fault diagnosis method based on Gaussian particle filter for autonomous underwater vehicles
Sun, Yu-shan,Ran, Xiang-rui,Li, Yue-ming,Zhang, Guo-cheng,Zhang, Ying-hao The Society of Naval Architects of Korea 2016 International Journal of Naval Architecture and Oc Vol.8 No.3
Autonomous Underwater Vehicles (AUVs) generally work in complex marine environments. Any fault in AUVs may cause significant losses. Thus, system reliability and automatic fault diagnosis are important. To address the actuator failure of AUVs, a fault diagnosis method based on the Gaussian particle filter is proposed in this study. Six free-space motion equation mathematical models are established in accordance with the actuator configuration of AUVs. The value of the control (moment) loss parameter is adopted on the basis of these models to represent underwater vehicle malfunction, and an actuator failure model is established. An improved Gaussian particle filtering algorithm is proposed and is used to estimate the AUV failure model and motion state. Bayes algorithm is employed to perform robot fault detection. The sliding window method is adopted for fault magnitude estimation. The feasibility and validity of the proposed method are verified through simulation experiments and experimental data.
Chi, Yu-Yang,Shen, Jing-Lin,Zhang, Jing,Shan, An-Shan,Niu, Shu-Ling,Zhou, Chang-Hai,Lee, Hong-Gu,Jin, Yong-Cheng Korean Society of Food Science and Technology 2016 Food Science and Biotechnology Vol.25 No.4
The aim of this study is to reveal the relation among villin 2, $Wnt/{\beta}-catenin$, and adipogenesis by adding appropriate lithium chloride (LiCl). The study comprises three parts: the selection of LiCl concentration, the effect of LiCl on adipocyte differentiation during and after differentiation induction. By comprehensively analyzing the results of the experiments, we proved that LiCl can inhibit adipocyte differentiation and enhance villin 2 and ${\beta}-catenin$ expressions not only during differentiation induction but also after it. Moreover, villin 2 has a significant impact on ${\beta}-catenin$. We suggest that villin 2 may participate in $Wnt/{\beta}-catenin$ signaling.