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RISS 인기검색어
- 검색키워드
- 저자 : Yongle Lu (검색결과 3 건)
- 무료
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- 유료
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High Shock-Resistant Design of Piezoresistive High-g Accelerometer
Yongle Lu,Zhen Qu,Jie Yang,Wenxin Wang,Wenbo Wang,Yu Liu 한국정보처리학회 2023 Journal of information processing systems Vol.19 No.2
To improve the shock-resistance of piezoresistive high-g accelerometer, we propose a design of piezoresistivehigh-g accelerometer. The accelerometer employs special-shaped proof masses system with a cross gap. Fourtiny sensing beams are bonded above the cross gap. The expression of the deformation, natural frequency anddamping is deduced, and the structural parameters are optimized. The accelerometer structure is simulated andverified by finite element method (FEM) simulation. The results show that the range of the accelerometer canreach 200,000 g, the natural frequency is 453.6 kHz, and the cross-axis sensitivity of X-axis and Y-axis is0.25% and 0.11%, respectively, which can apply to the measurement of high shock. Contrastively, the crossaxissensitivity of X-axis and Y-axis is respectively, reduced by 93.2% and 96.9%. The sensitivity of ouraccelerometer is 0.88 μV/g. It is of great value for the application of piezoresistive high-g accelerometer withhigh shock-resistance.
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YONGLING FANG,SONG XU,ZHONGYU LI,DANAN HAN,DAYONG LU 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.3
A 1,3-bis[(3,3-dimethylindolin-2-ylidene)methyl]squaraine (ISQ) dye sensitized ZnO nanocompo-sites via two di®erent preparation methods including hydrothermal and ultrasonic sensitizationprocesses are discussed in this paper. The as-prepared composites were characterized by the X-raydi®raction (XRD), UV-Vis di®use re°ectance spectroscopy (DRS), Raman spectroscopy, andtransmission electron microscopy (TEM). Based on the XRD patterns and TEM images, the ISQ/ZnO nanocomposites still kept the characteristic peaks and the basic morphology of ZnO and ISQdye. The photocatalytic activity of ISQ/ZnO nanocomposites was investigated by degradingmethylene blue (MB) under visible-light illumination. Compared with the MB self-degradation rate,the photocatalytic activity of the ISQ/ZnO composites was enhanced remarkably. The ISQ/ZnOnanocomposites fabricated by ultrasonic sensitization method exhibited excellent photocatalyticdegradation rate, approximately 20% higher than that of the hydrothermal sensitization one.
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The discovery of potent immunostimulatory CpG-ODNs widely distributed in bacterial genomes
Juan Liu,Yan Wei,Yongling Lu,Yangyuling Li,Qian Chen,Yan Li 한국미생물학회 2020 The journal of microbiology Vol.58 No.2
Oligodeoxynucleotides containing unmethylated CpG dinucleotides (CpG-ODN) can be specifically recognized by Toll-like receptor 9 (TLR9), provoking innate immune responses. Designed according to this structural feature, many synthetic phosphorothioate CpG-ODNs successfully activate macrophages. However, it is difficult to find potent stimulatory CpG-DNA fragments in microbial genomes. Therefore, whether microbial CpG-DNA substantially contributes to infectious and immune diseases remains controversial. In this study, high-throughput scanning was carried out for thousands of bacterial genomes with bioinformatics tools to comprehensively evaluate the distribution of CpG-DNA fragments. A random sampling test was then performed to verify their immunostimulatory properties by experiments in vitro and in vivo. Natural TLR9-dependent and potent stimulatory CpG-DNA fragments were found in microbial genomes. Interestingly, highly conserved stimulatory CpG-DNA fragments were found in 16S and 23S rDNA sequences with multiple copies, while others were species-specific. Additionally, we found that the reported active motifs were mostly nonstimulatory in natural CpG fragments. This evidence indicates that the previous structural descriptions of functional CpG-ODNs are incomplete. Our study has assessed the distribution of microbial CpG-DNA fragments, and identified natural stimulatory CpG-DNA fragments. These findings provide a deeper understanding of CpG-ODN structures and new evidence for microbial DNA inflammatory function and pathogenicity.
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