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Zhao, Lili,Li, Yongkun The Korean Society for Computational and Applied M 2013 Journal of applied mathematics & informatics Vol.31 No.3
In this paper, we study the global stability and the existence of almost periodic solution of high-order Hopfield neural networks with distributed delays of neutral type. Some sufficient conditions are obtained for the existence, uniqueness and global exponential stability of almost periodic solution by employing fixed point theorem and differential inequality techniques. An example is given to show the effectiveness of the proposed method and results.
Lili Zhao,Yongkun Li 한국전산응용수학회 2013 Journal of applied mathematics & informatics Vol.31 No.3
In this paper, we study the global stability and the existence of almost periodic solution of high-order Hopfield neural networks with distributed delays of neutral type. Some sufficient conditions are obtained for the existence, uniqueness and global exponential stability of almost periodic solution by employing fixed point theorem and differential inequality techniques. An example is given to show the effectiveness of the proposed method and results.
Yuetao Li,Yongkun Zhao,Cuiling Wang,Xuexing Zheng,Hualei Wang,Weiwei Gai,Hongli Jin,Feihu Yan,Boning Qiu,Yuwei Gao,Nan Li,Songtao Yang,Xianzhu Xia 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.2
Rift Valley fever (RVF) is an acute, febrile zoonotic disease that is caused by the RVF virus (RVFV). RVF is mainly prevalent on the ArabianPeninsula, the African continent, and several islands in the Indian Ocean near southeast Africa. RVFV has been classified by the WorldOrganisation for Animal Health (OIE) as a category A pathogen. To avoid biological safety concerns associated with use of the pathogen inRVFV neutralization assays, the present study investigated and established an RVFV pseudovirus-based neutralization assay. This study usedthe human immunodeficiency virus (HIV) lentiviral packaging system and RVFV structural proteins to successfully construct RVFVpseudoviruses. Electron microscopy observation and western blotting indicated that the size, structure, and shape of the packagedpseudoviruses were notably similar to those of HIV lentiviral vectors. Infection inhibition assay results showed that an antibody against RVFVinhibited the infective ability of the RVFV pseudoviruses, and an antibody neutralization assay for RVFV detection was then established. Thisstudy has successfully established a neutralization assay based on RVFV pseudoviruses and demonstrated that this method can be used toeffectively evaluate antibody neutralization.
Screening a Panel of Acid-producing Strains by Developing a High-throughput Method
Lijuan Zhu,Hui Zhang,Shiyuan Wang,Anqi Zhao,Lingbo Qu,Wenlong Xiong,Md. Asraful Alam,Wenlong Ma,Yongkun Lv,Jingliang Xu 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.5
Organic acids are natural cellular metabolites, which are widely used in food, pharmaceutical, and chemical industries. Among them, L-lactic acid is of special interest, because it is widely used in food and pharmaceutical industries and its monopolymer (poly (lactic acid)) is a green, renewable, biodegradable, and biocompatible alternative to the petroleum-based polymers. Currently, organic acids are predominantly produced by microbial fermentation. Their productions have been substantially improved by genetic modifications, metabolic engineering, and fermentation optimizations. However, the commonly used microbial producers still suffer from low acidic tolerance. Screening higher tolerant acid-producing microorganisms from the nature is relatively less explored. The traditional fermented foods are good resources for the screening of acid-producing and probiotic microorganisms. However, they are relatively less explored, especially those foods in developing countries. To speed up the acid-producing microorganism screening, we developed and validated a high-throughput method in this study. By using this method, we screened 1,296 colonies in 4 days and obtained a panel of acid-producing microorganisms. Among them, a Lacticaseibacillus rhamnosus showed the potential for organic acid production and probiotics applications.