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RISS 인기검색어
- 검색키워드
- 저자 : Yongbo Qiao (검색결과 3 건)
- 무료
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Yaguo Li,Yongbo Wu,Libo Zhou,Masakazu Fujimoto,Jian Wang,Qiao Xu,Shoichi Sasaki,Masaaki Kemmochi 한국정밀공학회 2014 International Journal of Precision Engineering and Vol.15 No.5
Vibration-assisted grinding, in which harder abrasives than materials to be machined are employed, has been a viable and effective approach to increasing material removal rate (MRR) and/or reducing surface roughness of ground surfaces. We transfer this ideology to fused silica polishing by incorporating ultrasonic vibration into recently developed fixed-abrasive pellets in an attempt to enhance MRR and/or to improve manufactured surface quality. A prototype ultrasonic vibrator, the heart of the polishing head, was designed and the related experimental work was performed on an in-house built setup in conjunction with the constructed head. The vibrator is devised for the generation of 2-D tool path despite using only one actuator in lieu of two actuators in conventional 2-D ultrasonic machining systems. We then combined the ultrasonic vibration with fixed abrasive polishing pellets to machine fused silica glass. Machining experiments reveal that MRR is considerably increased up to >50% upon the introduction of ultrasonic vibration (UV) whilst surface roughness is not degraded appreciably. It was also noted that a overwhelmingly greater deal of polishing debris was dispelled during ultrasonic vibration assisted polishing than conventional bound-abrasive polishing, which may account for the greater MRR in UV assisted polishing.
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Yaguo Li,Yongbo Wu,Libo Zhou,Masakazu Fujimoto,Jian Wang,Qiao Xu,Shoichi Sasaki,Masaaki Kemmochi 한국정밀공학회 2012 International Journal of Precision Engineering and Vol. No.
Vibration-assisted grinding, in which harder abrasives than materials to be machined are employed, has been a viable and effective approach to increasing material removal rate (MRR) and/or reducing surface roughness of ground surfaces. We transfer this ideology to fused silica polishing by incorporating ultrasonic vibration into recently developed fixed-abrasive pellets in an attempt to enhance MRR and/or to improve manufactured surface quality. A prototype ultrasonic vibrator, the heart of the polishing head, was designed and the related experimental work was performed on an in-house built setup in conjunction with the constructed head. The vibrator is devised for the generation of 2-D tool path despite using only one actuator in lieu of two actuators in conventional 2-D ultrasonic machining systems. We then combined the ultrasonic vibration with fixed abrasive polishing pellets to machine fused silica glass. Machining experiments reveal that MRR is considerably increased up to >50% upon the introduction of ultrasonic vibration (UV)whilst surface roughness is not degraded appreciably. It was also noted that a overwhelmingly greater deal of polishing debris was dispelled during ultrasonic vibration assisted polishing than conventional bound-abrasive polishing, which may account for the greater MRR in UV assisted polishing.
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Shuang Li,Bo Wang,Shun Jiang,Xiaohui Lan,Yongbo Qiao,Jiaojiao Nie,Yuhe Yin,Yuhua Shi,Wei Kong,Yaming Shan 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.1
Background: Porcine circovirus type 2 (PCV2) is an important infectious pathogen implicated in porcine circovirus-associated diseases (PCVAD), which has caused significant economic losses in the pig industry worldwide. Objectives: A suitable viral vector-mediated gene transfer platform for the expression of the capsid protein (Cap) is an attractive strategy. Methods: In the present study, a recombinant adeno-associated virus 8 (rAAV8) vector was constructed to encode Cap (Cap-rAAV) in vitro and in vivo after gene transfer. Results: The obtained results showed that Cap could be expressed in HEK293T cells and BABL/c mice. The results of lymphocytes proliferative, as well as immunoglobulin G (IgG) 2a and interferon-γ showed strong cellular immune responses induced by Cap-rAAV. The enzyme-linked immunosorbent assay titers obtained and the IgG1 and interleukin-4 levels showed that humoral immune responses were also induced by Cap-rAAV. Altogether, these results demonstrated that the rAAV8 vaccine Cap-rAAV can induce strong cellular and humoral immune responses, indicating a potential rAAV8 vaccine against PCV2. Conclusions: The injection of rAAV8 encoding PCV2 Cap genes into muscle tissue can ensure long-term, continuous, and systemic expression.
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