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RISS 인기검색어
- 검색키워드
- 저자 : Yerin Hyun(Yerin Hyun) (검색결과 35 건)
- 무료
- 기관 내 무료
- 유료
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Hayeon Kim(Hayeon Kim),Bumhee Park(Bumhee Park),Shin-Young Kim(Shin-Young Kim),Jiyea Kim(Jiyea Kim),Bora Kim(Bora Kim),Kyu-In Jung(Kyu-In Jung),Seung-Yup Lee(Seung-Yup Lee),Yerin Hyun(Yerin Hyun),Bung 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.4
Objective: This research measures the regional GMV (rGMV) of the cerebellum, attention, Executive Function (EF) and we aimed to identify their correlation and sex differences in children and adolescents. Methods: Subjects comprised 114 children (male = 62, female = 52, 12.44 ± 2.99 years old) from South Korea. Participants were divided into three groups by age (age 6−9, 10−13, and 14−17). The Stroop Color and Word Test (SCWT), Wisconsin Card Sorting Test (WCST), and Advanced Test of Attention (ATA) were used to estimate executive function. Magnetic resonance imaging (MRI) images were analyzed with Regional Voxel-Based Morphometry Analysis. Results: The correlations between cerebellar rGMV and SCWT, WCST, and ATA subcategories showed difference by age and sex. In 6−9 age group, girls showed more overall correlations with cerebellar regions than boys, in WCST Categories Completed and ATA results. In age 10−13 group, more regions of cerebellum corresponded to SCWT subcategories in girls. Nevertheless, more correlation between cerebellar rGMV, WCST subcategories and some ATA subtests were observed in boys in the same age group. In the adolescent group, aged 14−17, boys showed more correlation with cerebellar rGMV, while girls showed little correlation. Conclusion: This study highlights that sex-different cerebellum maturation in adolescence might be correlated with EF and attention. These results provides evidence that cerebellum modulates higher cognitive functioning during child development.
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Changes in ecotoxicity of naphthalene and alkylated naphthalenes during photodegradation in water
Kang, Hyun-Joong,Jung, Yerin,Kwon, Jung-Hwan Pergamon Press 2019 Chemosphere Vol. No.
<P><B>Abstract</B></P> <P>Crude oil released into the environment contains many polycyclic aromatic hydrocarbons (PAHs). Alkylated PAHs are more abundant than unsubstituted PAHs and their toxicity is also of serious concern. Among the various physical, chemical, and biological weathering processes of crude oils, photodegradation is one of the most important for determining the environmental fate of oil residues. In this study, the photodegradation rate constants of naphthalene and alkylated naphthalenes were determined under simulated laboratory conditions at different temperature. Changes in the luminescence inhibition of <I>Aliivibrio fischeri</I>, as an indicator of the baseline toxicity, were observed in photodegradation mixtures. The major transformation products were also identified by gas chromatography–mass spectrometry. The photodegradation of naphthalene and the eight alkylated naphthalenes was described well by pseudo-first-order kinetics regardless of experimental temperature. The measured toxicity of the reaction mixtures obtained by photodegradative weathering slightly increased initially and then decreased with further weathering. In all cases, the observed toxicity was greater than accounted for by the parent compounds, indicating that the photodegradation products also contributed significantly to the overall toxicity of the mixtures. The identified photodegradation products were mostly oxygenated compounds such as alcohols, aldehydes, ketones, and quinones, which warrant further investigation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Toxicity changes of Naph and alkyl-Naph by photodegradation were studied. </LI> <LI> The observed photodegradation was well-explained by pseudo-first-order kinetics. </LI> <LI> The observed toxicity of Naph and alkyl-Naph was decreased by photodegradation. </LI> <LI> The toxic contribution by photodegradation products was significant. </LI> <LI> The identified photodegradation products were mainly oxygenated forms. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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