http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Yasuo Tsuda (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Tsuda, Tohru,Morimoto, Yasuo,Yamato, Hiroshi,Fujino, Akihiro,Hori, Hajime,Kido, Masamitsu,Higashi, Toshiaki,Tanaka, Isamu 가톨릭대학교 산업의학센터 2001 韓國의 産業醫學 Vol.40 No.1
The primary concern of our study is to elucidate the development and pathophysiological mechanisms of occupational and environmental lung disease. The results of these studies are applied in the field of occupational health. Therefore, particular focuses are; 1) To introduce molecular-biomarkers into the risk assessment system of occupational exposed particles, 2) To apply molecular-biomarkers into conventional research methods, for the purpose of preventing and detecting early effects caused by occupational exposure to particles. Among fibrous materials, asbestos has been shown to cause diseases such as asbestosis, lung cancer and mesothelioma. On the other hand, there are many industries utilizing asbestos because of the many advantages as an industrial resource. The attempt to replace asbestos by man-made mineral fibres (MMFs) is fast in making progress because the industrial and economic gains are becoming certain. MMFs are thought to possess the same adverse biological effects as asbestos because of their similar physiochemical properties. Current data are now available showing that the new MMFs are not all nuisance particulate. No epidemiological studies are involving MMFs, and the results of animal studies on the adverse effects of MMFs are conflicting. Moreover, the toxic potentials of MMFs developed most are recently not always understood. Asia is a region which depends heavily on industrial development to sustain its growing population. Risk assessment of MMFs is a justifiable strategy to adopt particularly in this region. We have been constructing the risk assessment system of MMFs along following steps: study of physicochemical properties (1), in vitro study, intratracheal instillation study and acute to chronic inhalation study. We have compared the results of these steps with individual step and reached the final decision of toxicity to human. On the other hand, lung is one of the most important organ that is directly contact with the work environment. For this reason, factors concerning pathogenesis of occupational or work-related lung disease would be multiple. Thus, evaluating the environmental factors including smoking are also important.
-
Satoshi Ida,Naoki Hiki,Takeaki Ishizawa,Yugo Kuriki,Mako Kamiya,Yasuteru Urano,Takuro Nakamura,Yasuo Tsuda,Yosuke Kano,Koshi Kumagai,Souya Nunobe,Manabu Ohashi,Takeshi Sano 대한위암학회 2018 Journal of gastric cancer Vol.18 No.2
Purpose: Postoperative pancreatic fistula is a serious and fatal complication of gastrectomy for gastric cancer. Blunt trauma to the parenchyma of the pancreas can result from an assistant's forceps compressing and retracting the pancreas, which in turn may result in pancreatic juice leakage. However, no published studies have focused on blunt trauma to the pancreas during laparoscopic surgery. Our aim was to investigate the relationship between compression of the pancreas and pancreatic juice leakage in a swine model. Materials and Methods: Three female pigs were used in this study. The pancreas was gently compressed dorsally for 15 minutes laparoscopically with gauze grasped with forceps. Pancreatic juice leakage was visualized by fluorescence imaging after topical administration of chymotrypsin-activatable fluorophore in real time. Amylase concentrations in ascites collected at specified times was measured. In addition, pancreatic tissue was fixed with formalin, and the histology of the compressed sites was evaluated. Results: Fluorescence imaging enabled visualization of pancreatic juice leaking into ascites around the pancreas. Median concentrations of pancreatic amylase in ascites increased from 46 U/L preoperatively to 12,509 U/L 4 hours after compression. Histological examination of tissues obtained 4 hours after compression revealed necrotic pancreatic acinar cells extending from the surface to deep within the pancreas and infiltration of inflammatory cells. Conclusions: Pancreatic compression by the assistant's forceps can contribute to pancreatic juice leakage. These findings will help to improve the procedure for lymph node dissection around the pancreas during laparoscopic gastrectomy.
-
Ida, Satoshi,Hiki, Naoki,Ishizawa, Takeaki,Kuriki, Yugo,Kamiya, Mako,Urano, Yasuteru,Nakamura, Takuro,Tsuda, Yasuo,Kano, Yosuke,Kumagai, Koshi,Nunobe, Souya,Ohashi, Manabu,Sano, Takeshi The Korean Gastric Cancer Association 2018 Journal of gastric cancer Vol.18 No.2
Purpose: Postoperative pancreatic fistula is a serious and fatal complication of gastrectomy for gastric cancer. Blunt trauma to the parenchyma of the pancreas can result from an assistant's forceps compressing and retracting the pancreas, which in turn may result in pancreatic juice leakage. However, no published studies have focused on blunt trauma to the pancreas during laparoscopic surgery. Our aim was to investigate the relationship between compression of the pancreas and pancreatic juice leakage in a swine model. Materials and Methods: Three female pigs were used in this study. The pancreas was gently compressed dorsally for 15 minutes laparoscopically with gauze grasped with forceps. Pancreatic juice leakage was visualized by fluorescence imaging after topical administration of chymotrypsin-activatable fluorophore in real time. Amylase concentrations in ascites collected at specified times was measured. In addition, pancreatic tissue was fixed with formalin, and the histology of the compressed sites was evaluated. Results: Fluorescence imaging enabled visualization of pancreatic juice leaking into ascites around the pancreas. Median concentrations of pancreatic amylase in ascites increased from 46 U/L preoperatively to 12,509 U/L 4 hours after compression. Histological examination of tissues obtained 4 hours after compression revealed necrotic pancreatic acinar cells extending from the surface to deep within the pancreas and infiltration of inflammatory cells. Conclusions: Pancreatic compression by the assistant's forceps can contribute to pancreatic juice leakage. These findings will help to improve the procedure for lymph node dissection around the pancreas during laparoscopic gastrectomy.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
