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        Macroscopic Zn-doped a-Fe2O3/graphene aerogel mediated persulfate activation for heterogeneous catalytic degradation of sulfamonomethoxine wastewater

        Shuying Dong,Xuanxuan Yan,Wenli Li,Yafei Liu,Xiaoxu Han,Xiaodan Liu,Jinglan Feng,Chongfei Yu,Chunyan Zhang,Jianhui Sun 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.108 No.-

        In order to obtain a robust, durable and efficient heterogeneous catalyst, macroscopic monolithic Zndopeda-Fe2O3/graphene aerogel (GA) hybrid architecture with integrated morphology and hierarchicallyporous structure were controllably synthesized via a facile in-situ hydrothermal method and then used aspersulfate (PS) activator for sulfamonomethoxine (SMM) wastewater purification. Several key reactionparameters including the initial SMM concentration, reaction temperature, coexisting inorganic anionsand SMM in real natural water samples had different influence on the SMM removal efficiency. The catalyticefficiency of Zn-doped a-Fe2O3/GA with the molar ratio of Fe/Zn = 2:1.5 was about 66%, 62%, 66%and 11%33% higher than that of GA, a-Fe2O3/GA, Zn/GA and other Fe/Zn molar ratio. The improvedactivity of Fe/Zn = 2:1.5 benefits from the synergistic effects of the sp2 hybridized carbon and porousframework, as well as the surface oxygenic functional groups, which accelerate the pollutant/oxidant dispersionand electron transfer. Electron paramagnetic resonance results indicate that OH, 1O2 and SO4radicals account for the catalytic degradation of SMM and the activation of PS in present system is differentfrom conventional homogeneous systems, and speculate mechanism was proposed based on theobtained data.

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        Downstream Neighbor of Son Overexpression is Associated With Breast Cancer Progression and a Poor Prognosis

        Yufeng Qi,Haodong Wu,Conghui Liu,Danni Zheng,Congzhi Yan,Wenjing Hu,Xiaohua Zhang,Xuanxuan Dai 한국유방암학회 2022 Journal of breast cancer Vol.25 No.4

        Purpose: The incidence rate of breast cancer (BC) has increased annually. Downstream neighbor of son (DONSON) critically affects cell cycle progression and maintains stable genomic properties; however, its relevant effects on BC growth and progression require in-depth investigation. Methods: DONSON upregulation was validated in public databases. DONSON expression in matched BC and adjacent tissues and cell lines (MDA-MB-231, BT-549, and HS-578T) was determined using quantitative reverse transcription polymerase chain reaction. In vitro apoptosis, invasion, migration, and proliferation tests were performed to ascertain the functions of DONSON in BC cell lines. Then, using western blot analysis, the levels of DONSON downstream proteins were determined. Results: Compared to the control, DONSON was expressed at higher levels in BC tissues and cell lines. DONSON knockdown facilitated apoptosis and limited proliferation, migration, invasion, and S/G2 transition of BC cells in vitro. Furthermore, DONSON overexpression promoted BC cell proliferation and inhibited apoptosis in vitro. Moreover, DONSON knockdown reduced cyclin A1 and cyclin-dependent kinase 2 levels. Moreover, DONSON knockdown limited the progression of epithelial-mesenchymal transition. Conclusion: DONSON critically affects BC growth and serves as a possible target and marker for the efficacy of subsequent therapies.

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        Investigation of melting dynamics of filler wire during wire feed laser welding

        Yangchun Yu,Wei Huang,Guozhen Wang,Jun Wang,Xuanxuan Meng,Chunming Wang,Fei Yan,Xiyuan Hu,Shengfu Yu 대한기계학회 2013 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.27 No.4

        In order to investigate the mechanism of stability for the wire feed laser welding process, systematic experiments are carried out in this study for 5A06 aluminum alloy. By using high speed camera, the melting dynamics of filler wires with different feed positions and feed rates are studied. The results indicate that these two factors mainly influence the characteristics of the filler wire melting dynamics and determine the stability of the welding process. The melting dynamics of filler wire can be generally characterized by three different forms: explosion, big droplet and molten metal bridge. When the filler wire melts and transits to the molten pool in the forms of explosion or big droplet, the stability of the welding process is strongly disturbed, resulting in an undesirable weld quality. In contrast, when it is in molten metal bridge form, the welding process is more stable and a uniform weld bead is achieved.

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