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- 저자 : Witte, Frank (검색결과 44 건)
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Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus.
Witte, Hanh,Moreno, Eduardo,R?delsperger, Christian,Kim, Jungeun,Kim, Jin-Soo,Streit, Adrian,Sommer, Ralf J Springer-Verlag 2015 Development genes and evolution Vol.225 No.1
<P>The diplogastrid nematode Pristionchus pacificus is a nematode model system for comparative studies to Caenorhabditis elegans and integrative evolutionary biology aiming for interdisciplinary approaches of evo-devo, population genetics, and ecology. For this, fieldwork can be combined with laboratory studies, and P. pacificus has a well-developed methodological toolkit of forward genetics, whole genome sequencing, DNA-mediated transformation, and various -omics platforms. Here, we establish CRISPR/Cas9-based gene inactivation and describe various boundary conditions of this methodology for P. pacificus. Specifically, we demonstrate that most mutations arise within the first 9 hours after injections. We systematically tested the efficiency of sgRNAs targeting different exons in Ppa-dpy-1 and characterized the molecular nature of the induced mutations. Finally, we provide a protocol that might also be useful for researchers working with other non-Caenorhabditis nematodes.</P>
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Witte, Herman 단국대학교 산업연구소 1980 산업연구 Vol.2 No.-
「포트휠리오」결정을 분석함에 있어서 「포트휠리오」 배분리론은 금전적보수를 고려하고 잇다 「토빈」(Tobin)의 접근방법에 있어서는 위험이 포함되고 있으며 비화폐결정기준은 등한시되고 있는데 이로 인하여 이론적 파급 메카니즘개념의 기초로서 「포트휠리오」결정을 불완전하게 하고 있다. MPD분석은 이 결함을 보완하기 위함이며 의사결정이론의 근대적방법에 의거 비화폐적 요소를 고려하여 설명되었다. 경제부문에 특수한 목표를 상정하고 대립되는 「포트휠리오」를 평가하기 위하여 결정개준이 도출되었다. 비화폐적겨정기준을 화폐화하기 위하여 경제이론중에서 변형전선을 이용하고 목표의 도출은 경제이론중 다른 범주에 속한 전반적 목표이론(Goal Theory)에 의거하였다. MPD분석에 대하여 적절한 목표가 전개되었으며 모든 결제부문에 적용되는 MPD분석의 접근방법이 전반적 경제연합을 설명할 수 있는가 그리고 결제정책의 효과분석에 대하여서는 단지 간략히 언급하였다.
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Asian Exchange Rates during the Credit Crisis: Policies to Avoid Depreciation
Mark David Witte 연세대학교 동서문제연구원 2010 Global economic review Vol.39 No.1
A few policy recommendations become apparent to avoid depreciation relative to other regional currencies when examining intra-Asian exchange rates during the most recent credit crisis. One, avoid large fiscal deficits. Two, avoid high inflation and current account deficits in order to maintain low interest rates to avoid depreciation from the unwinding of the carry trade. Third, build large official reserves or, more importantly, build large reserves of foreign currency assets. Additional results show an unexplained depreciation of the Australian dollar and the Indian rupee and appreciation of the Thai baht as the TED spread widened and credit crisis worsened.
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Currency Invoicing: The Role of 'Herding' and Exchange Rate Volatility
Mark David Witte 한국국제경제학회 2010 International Economic Journal Vol.24 No.3
This paper analyzes an individual firm's choice of invoicing currency under exchange rate volatility. Greater exchange rate volatility amplifies the representative firm's desire to 'herd' relative to all other considerations that may affect the currency denomination decision. By 'herding' a firm chooses a currency of denomination so that the firm's price and the competition's price are affected by the exchange rate in a similar manner. Contrary to previous research, the results herein suggest that individual firms may invoice in a relatively volatile currency as long as its competitor's invoice in the same volatile currency.
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When is a global currency optimal?
Mark David Witte 연세대학교 동서문제연구원 2009 Global economic review Vol.38 No.1
The purpose of this paper is to examine what factors make an individual, exporting firm choose to denominate its price(s) in the same currency for multiple markets in different countries. The unique model herein maintains an endogenous frequency of price adjustment, price discrimination and currency of denomination. The representative firm is likely to choose a global price (one price in one currency for all countries) based mostly on macroeconomic and industry-specific characteristics. Exchange rate transaction costs, exchange rate volatility and market size consistently impact the optimality of the use of a global currency.
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An Empirical Examination of the Currency Denomination of Trade
Mark David Witte,Luigi Ventura 한국국제경제학회 2016 International Economic Journal Vol.30 No.1
The currency denomination of trade has important effects on inflation and the macroeconomic transmission of shocks. This study examines the currency denomination of Italian exports and imports with countries outside the European Union during 2010. By using a unique dataset we find evidence to suggest that invoicing currencies do not always have consistent determinants. Significant effects, new to the literature, include the massive, robust effect of geography and tax treaties, which suggest the importance of information asymmetry. The distance between trading partners has one of the largest marginal effects, increasing the likelihood of vehicle currency use relative to the euro.
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Voigt, Fritz,Witte, Hermann 단국대학교 산업연구소 1980 산업연구 Vol.2 No.-
교통론도 여타 과학과 마찬가지로 그 과학적 원리에 있어서는 방법론적으로 복수주의가 채택된다. 그러기 때문에 전 경제적 입장에서 본 여타부문 상호간이나 교통정책 수행과정의 분석을 위하여 여러가지의 이론이 서로 관련을 가지게 된다. 일반적인 교통이론을 설명하고 교통이론의 근본적인 요소를^1) 정확히 서술하려는 시도가 본 연구의 목적이다. 따라서 한 교통제도에서 부터 파급되는 경제전체의 교통분석을 위한 하나의 포괄적인 시도가 다음에 설명하는 교통이론에서 다루어 질것이다. 한 경제사회제도 내에서 본 논문이 전개하는 교통정책의 특징이란 교통부문의 국민경제적 의의를 살린 일반적 이론의 전제조건을 말한다.
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Ventura Luigi,Witte Mark David 한국국제경제학회 2024 International Economic Journal Vol.38 No.1
This paper examines the impact of Euro invoicing on Italian exports to non-EU countries. In addition to examining the role of currency invoicing on the intensive and extensive margin of trade, we introduce the ‘entrenched’ margin of trade. We define the entrenched margin of trade as the number of transactions between two countries of a particular good. With highly disaggregated data, we use a two-stage methodology to predict the probability of Euro dominated Italian exports and then use that predicted probability on the intensive, extensive and entrenched margin of trade. Results show that the probability of Euro dominated trade invoicing reduces all three margins of trade. Specifically, a 10% increase in probability of Euro dominated Italian exports has roughly the same impact as additional 1532 km on the intensive margin of trade, 1096 km on the extensive margin of trade and 1314 km on the entrenched margin of trade. The negative effect of Euro invoicing is most consistent with lowermiddle income trading partners and more thinly traded goods. We surmise that these results are due to varying access to financial instrumentation among Italian trade partners and a trade diversion effect of Italian exports to EU countries versus non-EU markets.
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