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RISS 인기검색어
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- 저자 : Vishnu Sharma (검색결과 5 건)
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Vishnu Baburaj,Sandeep Patel,Vishal Kumar,Siddhartha Sharma,Mandeep Singh Dhillon 대한견주관절의학회 2024 대한견주관절의학회지 Vol.27 No.1
Background: Clinical outcomes after fixation of distal humerus intraarticular fractures are directly related to the quality of reduction. The use of three-dimensional (3D)-printed fracture models can benefit preoperative planning to ensure good reduction. This review aims to determine if surgery performed with 3D printing assistance are faster and result in fewer complications and improved clinical outcomes than conventional methods. We also outline the benefits and drawbacks of this novel technique in surgical management of distal humerus fractures. Methods: A systematic literature search was carried out in various electronic databases. Search results were screened based on title and abstract. Data from eligible studies were extracted into spreadsheets. Meta-analysis was performed using appropriate computer software. Results: Three randomized controlled trials with 144 cases were included in the final analysis. The 3D-printed group had significantly shorter mean operating time (mean difference, 16.25 minutes; 95% confidence interval [CI], 12.74–19.76 minutes; P<0.001) and mean intraoperative blood loss (30.40 mL; 95% CI, 10.45–60.36 mL; P=0.005) compared with the conventional group. The 3D-printed group also tended to have fewer complications and a better likelihood of good or excellent outcomes as per the Mayo elbow performance score, but this did not reach statistical significance. Conclusions: Three-dimensional-printing-assisted surgery in distal humerus fractures has several benefits in reduced operating time and lower blood loss, indirectly decreasing other complications such as infection and anemia-related issues. Future good-quality studies are required to conclusively demonstrate the benefits of 3D printing in improving clinical outcomes.
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Gogia, Ajay,Raina, Vinod,Deo, Suryanarayan Vishnu,Shukla, Nootan Kumar,Mohanti, Bidhu Kalyan,Sharma, Daya Nand Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.5
Background: The aim of this study was to assess the response rates (clinical and pathological ) with docetaxel and epirubicin combination chemotherapy and its effect on outcome. Materials and Methods: We retrospectively analysed locally advanced breast cancer (LABC) patients who received NACT from January 2008 to December 2012 in our tertiary care centre. LABC constituted 37% of all breast cancer cases and 120 patients fulfilled the eligibility criteria. The regimens used for NACT were, six cycles of DEC (docetaxel $75mg/m^2$, epirubicin $75mg/m^2$, cyclophosphamide $50mg/m^2$ on Day 1, 3 weekly) and a sequential regimen (4 cycles of FEC, 5-flurouracil $600mg/m^2$, epirubicin $75mg/m^2$, cyclophosphamide $600mg/m^2$ followed by 4 cycles of docetaxel $85mg/m^2$). Results: The median age was 47 years (range 23-72). Ninety six ( 80 %) had T4 disease and 90% had clinically palpable lymph nodes at diagnosis. The median size of primary tumor at presentation was 5.9 cm. Hormone receptor positivity was seen in 55% and HER2/neu positivity, in 25%. Triple negative breast cancers constituted 25 % of the cases. The overall clinical response rate (complete or partial ) was 85% and pathological complete responses were obtained in 15%. Four cases defaulted, 5 patients died of treatment related toxicity and 15% developed febrile neutropenia on DEC. The median duration of follow up was 22 months. The median time to relapse was 20 months and the 3 year relapse free and overall survival rates were 50% and 70% respectively. Conclusions: LABC constituted 37% of all breast cancer cases at our institute. With NACT, pCR was seen in 15% of the cases. Sequential chemotherapy was better tolerated than concurrent anthracyline and taxane chemotherapy with a similar pCR.
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Inflammatory Breast Cancer: a Single Centre Analysis
Gogia, Ajay,Raina, Vinod,Deo, Suryanarayan Vishnu,Shukla, Nootan Kumar,Mohanti, Bidhu Kalyan,Sharma, Daya Nand Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7
Background: Inflammatory breast cancer (IBC) is an aggressive form of locally advanced breast cancer characterized by rapidly progressive breast erythema, pain and tenderness, oedema and paeu d'orange appearance. It accounts for 1-3% of all newly diagnosed cases of breast cancer in the west. Data on IBC from India are lacking. The aim of our study was to assess the clinical-pathological parameters and outcome of IBC at, All India Institute of Medical Sciences, a large tertiary care centre. Materials and Methods: We screened 3,650 breast cancer cases registered from January 2004 to December 2012 and found 41 cases of IBC. Data included demographics as well as clinical, radiological and histopathological characteristics, and were collected from clinical case records using the International Classification of Diseases code (C-50). Patients who presented with IBC as a recurrence, or who had a neglected and advanced breast cancer that simulated an IBC were excluded from this study. Results: The median age was 45 years (range 23-66). The median duration of symptoms was 5 months. The American Joint Committee on Cancer stage (AJCC) distribution was Stage III - 26 and IV - 15 patients. Estrogen receptor (ER), progesterone receptor (PR) positivity and human epidermal growth factor receptor 2 (HER2/neu) positivity were 50%, 46% and 60%, respectively. Triple negativity was found in 15% of the cases. All the non metastatic IBC patients received anthracycline and/ or taxane based chemotherapy followed by modified radical mastectomy, radiotherapy and hormonal therapy as indicated. Pathological complete remission rate was 15%. At a median follow-up of 30 months, the 3 year relapse free survival and overall survival were 30% and 40%respectively. Conclusion: IBC constituted 1.1% of all breast cancer patients at our centre. One third of these had metastatic disease at presentation. Hormone positivity and Her2 neu positivity were found in 50% and 60% of the cases, respectively.
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FURTHER ON PETROVIĆ'S TYPES INEQUALITIES
IQBAL, WASIM,REHMAN, ATIQ UR,FARID, GHULAM,RATHOUR, LAXMI,SHARMA, M.K.,MISHRA, VISHNU NARAYAN The Korean Society for Computational and Applied M 2022 Journal of applied mathematics & informatics Vol.40 No.5-6
In this article, authors derived Petrović's type inequalities for a class of functions, namely, called exponentially h-convex functions. Also, the associated results for coordinates has been derived by defining exponentially h-convex functions on coordinates.
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Development of a Triggering Arrangement For the KALI-30GW MARX Generator
S. Mitra,T. S. Kolge,Ritu Agarwal,P. C. Saroj,Ankur Patel,K. Senthil,Vishnu Sharma,S. V. Tewari,Archana Sharma,K. C. Mittal 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.66 No.4
This paper reports the design methodology and implementation experiments for a solid-statebasedtriggering arrangement for the MARX generator of the KALI-30GW (1 MV, 30 kA, 80 ns)pulsed power system. The 15-stage bipolar MARX generator of the KALI-30GW system is triggeredusing a trigatron-type spark gap. An insulated-gate bipolar-transistor (IGBT)-based trigger supplyis used to trigger the first spark gap, and the next two spark gaps are triggered by using internallygeneratedtrigger pulses. Optically-isolated arrangements are provided for a human interface. Theentire assembly was tested with a dummy copper sulphate load, and an excellent triggering rangeof 7 − 12 kV was achieved. The circuit diagram, analysis and experimental results of the triggeringarrangement are presented in the paper.
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