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Monostotic Paget Disease of the Lumbar Vertebrae: A Pathological Mimicker
Vishnu Senthil,Satish Balaji 대한척추신경외과학회 2018 Neurospine Vol.15 No.2
Paget disease is a metabolic disorder involving abnormal bone turnover that consists of 3 phases: the initial lytic phase, the intermediate mixed phase, and the chronic sclerotic phase. Paget disease mostly presents as polyostotic or monostotic lesions of the spine, and is rare on the Indian subcontinent. We present a case of isolated Paget disease of the lumbar third vertebra, which was confirmed only at biopsy. The patient presented with chronic low backache with a developing neurological deficit. We managed the patient with posterior spinal stabilisation, using pedicular screws and vertebroplasty of the collapsed vertebrae to regain the height. Upon the diagnosis of Paget disease, the patient was treated with calcitonin and bisphosphonates for 3 months, along with regular monitoring of alkaline phosphatase levels. Through this case, we hope to emphasize that Paget disease should be considered in the differential diagnosis of lytic lesions. Additionally, the alkaline phosphatase level in this patient was high-normal, which was an aspect of the role of Paget disease as a mimicker. Confirmatory biopsy is mandatory in all lesions.
Development of a Triggering Arrangement For the KALI-30GW MARX Generator
S. Mitra,T. S. Kolge,Ritu Agarwal,P. C. Saroj,Ankur Patel,K. Senthil,Vishnu Sharma,S. V. Tewari,Archana Sharma,K. C. Mittal 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.66 No.4
This paper reports the design methodology and implementation experiments for a solid-statebasedtriggering arrangement for the MARX generator of the KALI-30GW (1 MV, 30 kA, 80 ns)pulsed power system. The 15-stage bipolar MARX generator of the KALI-30GW system is triggeredusing a trigatron-type spark gap. An insulated-gate bipolar-transistor (IGBT)-based trigger supplyis used to trigger the first spark gap, and the next two spark gaps are triggered by using internallygeneratedtrigger pulses. Optically-isolated arrangements are provided for a human interface. Theentire assembly was tested with a dummy copper sulphate load, and an excellent triggering rangeof 7 − 12 kV was achieved. The circuit diagram, analysis and experimental results of the triggeringarrangement are presented in the paper.