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- 저자 : Vafa Rahimi-Movaghar (검색결과 3 건)
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Epidemiology of Primary CNS Tumors in Iran: A Systematic Review
Jazayeri, Seyed Behzad,Rahimi-Movaghar, Vafa,Shokraneh, Farhad,Saadat, Soheil,Ramezani, Rashid Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Background: Although primary malignant CNS tumors are registered in the national cancer registry (NCR) of Iran, there are no available data on the incidence of the primary malignant or benign CNS tumors and their common histopathologies in the country. This study analyzed the 10-year data of the Iranian NCR from March 21, 2000 to March 20, 2010, including a systematic review. Materials and Methods: The international and national scientific databases were searched using the search keywords CNS, tumor, malignancy, brain, spine, neoplasm and Iran. Results: Of the 1,086 primary results, 9 papers were selected and reviewed, along with analysis of 10-year NCR data. The results showed that primary malignant brain tumors have an overall incidence of 2.74 per 100,000 person-years. The analysis of the papers revealed a benign to malignant ratio of 1.07. The most common histopathologies are meningioma, astrocytoma, glioblastoma and ependymoma. These tumors are more common in men (M/F=1.48). Primary malignant spinal cord tumors constitute 7.1% of the primary malignant CNS tumors with incidence of 0.21/100,000. Conclusions: This study shows that CNS tumors in Iran are in compliance with the pattern of CNS tumors in developing countries. The NCR must include benign lesions to understand the definitive epidemiology of primary CNS tumors in Iran.
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( Payman Salamati ),( Reza Rostami ),( Soheil Saadat ),( Taher Taheri ),( Maryam Tajabadi ),( Ghazale Ranjbari ),( Zohrehsadat Naji ),( Saba Jafarpour ),( Vafa Rahimi Movaghar ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Patients with spinal cord injury (SCI) have a lower health related quality of life (HRQOL) in comparison with both healthy controls and the normal population. The aim of this study was to compare HRQOL between two groups of veteran and non-veteran SCI patients. Methods: Male paraplegic non-veterans who had sustained complete SCI before the year 1988 and were residents of Tehran province, Iran, and a similar group of SCI veterans were enrolled in this study. The participants were interviewed based on the Iranian version of SF-36 questionnaire by two psychologists. Eight sub-scales and two physical and mental component summaries of the instrument were assessed. We used chi-square, odds ratio, Mann-Whitney U, independent t-test, and linear regression for analysis. Results: Overall, 25 veterans and 22 non-veterans were enrolled in the study. The mean age, time since injury, and presence of comorbid illnesses were not signifi cantly different between veterans and non-veterans. A greater number of veterans were married (P=0. 003) and employed (P=0. 047). On average, veterans had more years of formal education than non-veterans (P=0. 001). The mean (SD) bodily pain sub-scale was 72. 73(31. 253) for non-veterans and 49. 7(28. 287) for veterans (P=0. 011). Absence of comorbid illnesses was associated with a better physical component summary (P<0. 001). Employment was associated with a better mental component summary (P=0. 022). Conclusions: We did not fi nd any difference in HRQOL between the two groups except for the bodily pain sub-scale. Further studies with larger sample sizes are recommended.
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Amirmohammad Toloui,Hamzah Adel Ramawad,Pantea Gharin,Alexander R. Vaccaro,Hamed Zarei,Mostafa Hosseini,Mahmoud Yousefifard,Vafa Rahimi-Movaghar 대한척추신경외과학회 2023 Neurospine Vol.20 No.3
Objective: The objective of this systematic review and meta-analysis was to assess the efficacy of exercise in neuropathic pain following traumatic spinal cord injuries. Methods: The search was conducted in MEDLINE, Embase, Scopus, and Web of Science by the end of 2022. Two independent researchers included the articles based on the inclusion and exclusion criteria. A standardized mean difference was calculated for each data and they were pooled to calculate an overall effect size. To assess the heterogeneity between studies, I2 and chi-square tests were utilized. In the case of heterogeneity, meta-regression was performed to identify the potential source. Results: Fifteen preclinical studies were included. Meta-analysis demonstrated that exercise significantly improves mechanical allodynia (standardized mean difference [SMD], -1.59; 95% confidence interval [CI], -2.16 to -1.02; p < 0.001; I2 = 90.37%), thermal hyperalgesia (SMD, 1.95; 95% CI, 0.96–2.94; p < 0.001), and cold allodynia (SMD, -2.92; 95% CI, -4.4 to -1.43; p < 0.001). The improvement in mechanical allodynia is significantly more in animals with a compression model of SCI (meta-regression coefficient, -1.33; 95% CI, -1.84 to -0.57; p < 0.001) and in mild SCI (p < 0.001). Additionally, the improvement was more prominent if the training was started 7 to 8 days postinjury (coefficient, -2.54; 95% CI, -3.85 to -1.23; p < 0.001) and was continued every day (coefficient, -1.99; 95% CI, -3.07 to -0.9; p < 0.001). Likewise, voluntary exercise demonstrated a significantly more effect size (coefficient, -1.45; 95% CI, -2.67 to -0.23; p = 0.02). Conclusion: Exercise is effective in the amelioration of neuropathic pain. This effect in mechanical allodynia is more prominent if voluntary, continuous training is initiated in the subacute phase of mild SCI.
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