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RISS 인기검색어
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- 저자 : Umadevi C. (검색결과 2 건)
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Cascaded Fuzzy Logic Controlled Modular Multilevel Converter for PV Based DSTATCOM Applications
Umadevi C.,Sundari M. Gnana,Karuvelam P. Subha 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.3
This paper analyses the implementation of modular multi level converter (MMLC) in the application of grid connected Photovoltaic system in an efcient manner. As MMLC exhibits properties of high modularity and scalability, it is highly suitable for the high power applications, which makes MMLC to be preferred in this study as an apt replacement of the conventional DC–DC converters. A unifed control using a cascaded fuzzy logic controller (CFLC) is proposed for both the maximum power point tracking and modular 7 level converter (M7LC) control. The CFLC is analogized with the conventional PI and Fuzzy controllers under both the normal and partial shaded conditions. The entire system is assessed with the aid of using MATLAB simulation. The observed outcomes exhibit that total harmonic distortion (THD) of line current is minimum under all operating conditions when the CFLC is used for M7LC. The prototype of the proposed M7LC with CFLC is implemented in FPGA SPARTAN 6E controller for the experimental validation. The proposed approach delivers lesser THD of 1.02% under normal condition and 1.12% under partial shading condition.
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Ramasamy, T.,Poudel, B.K.,Ruttala, H.,Choi, J.Y.,Hieu, T.D.,Umadevi, K.,Youn, Y.S.,Choi, H.G.,Yong, C.S.,Kim, J.O. Elsevier 2016 Colloids and Surfaces B Vol.146 No.-
<P>Nanofabrication of polymeric micelles through self-assembly of an ionic block copolymer and oppositely charged small molecules has recently emerged as a promising method of formulating delivery systems. The present study therefore aimed to investigate the interaction of cationic drugs doxorubicin (DOX) and mitoxantrone (MTX) with the anionic block polymer poly(ethylene oxide)-block-poly(acrylic acid) (PEO-b-PAA) and to study the influence of these interactions on the pharmacokinetic stability and antitumor potential of the formulated micelles in clinically relevant animal models. To this end, individual DOX and MTX-loaded polyelectrolyte complex micelles (PCM) were prepared, and their physicochemical properties and pH-responsive release profiles were studied. MTX-PCM and DOX-PCM exhibited a different release profile under all pH conditions tested. MTX-PCM exhibited a monophasic release profile with no initial burst, while DOX-PCM exhibited a biphasic release. DOX-PCM showed a higher cellular uptake than that shown by MTX-PCM in A-549 cancer cells. Furthermore, DOX-PCM induced higher apoptosis of cancer cells than that induced by MTX-PCM. Importantly, both MTX-PCM and DOX-PCM showed prolonged blood circulation. MTX-PCM improved the AUC(all) of MTX 4-fold compared to a 3-fold increase by DOX-PCM for DOX. While a definite difference in blood circulation was observed between MTX-PCM and DOX-PCM in the pharmacokinetic study, both MTX-PCM and DOX-PCM suppressed tumor growth to the same level as the respective free drugs, indicating the potential of PEGylated polymeric micelles as effective delivery systems. Taken together, our results show that the nature of interactions of cationic drugs with the polyionic copolymer can have a tremendous influence on the biological performance of a delivery system. (C) 2016 Elsevier B.V. All rights reserved.</P>
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