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OUTREACH ACTIVITY USING THE INTERNET TELESCOPE
UEDA, HARUHIKO,YAMAMOTO, YUKI,OMOTE, MINORU,SAKODA, SEIJI,TODA, KOUICHI The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2
We here report on the outreach activity using the Keio University Internet telescope performed by Science agora 2012 and 2013 in Tokyo. Many visitors came to our booth and operated the Keio University Internet telescope, and our project was awarded the prize of the National Institute of Advanced Industrial Science and Technology. In addition, based on the questionnaire for that occasion, the usefulness of the Internet telescopes in outreach activities is considered.
Control and Mechanism of Tumor Promotion in UV-Carcinogenesis
Ueda, Masato,Budiyanto, Arief,Ashida, Masashi,Bito, Toshinori,Ichihashi, Masamitsu Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Carcinogenesis can be theoretically divided to intiation step and promotion step. Intiation associates with genetic alterations including p53 tumor suppressor gene and ras oncogene. Promotion involves in clonal expansion of of an initiated cell by epigenetic mechanism, mainly through signal transduction and gene expression. Ultraviolet light (UV) acts as both initiator and promoter. Initiation is closely related with DNA damage induced by UV, including cyclobutane pyrimidine dimers, (6-4) photoproducts and 8-hydroxy-2'-deoxyguanosine. Cyclobutane pyrimidine dimers and (6-4) photoproducts are directly induced by UV, while 8-hydroxy-2'-deoxyguanosine is induced indirectly by the reactive oxygen species. Because initiation is an irreversal genetic event, while promotion is a reversal and epigenetic event, to know the molecular mechanisms of tumor promotion in UV-carcinogenesis is crucial to develop preventive medicine and suppress UV-carcinogenesis. Because ROS is also involved in signal transduction of the cell, anti-oxidant could be the good candidate of anti-promoting agent. Here, we describe the suppressive effect of UV-carcinogenesis by various anti-oxidant including olive oil. In addition, we discuss about the mechanism of UVB-induced expression of cyclooxygenase-2, which might be a representative molecule involved in promotion of UV-carcinogenesis.
Evaluation of 131I (monoiodide) BSP for Clinical Studies
Ueda, Hideo,Iro, Masahiro,Kurata, Kunio,Yamada, Hideo,Iwase, Tohru,Migita, Tohru,Kameda, Haruo,Kato, Sadatake,Sato, Noboru,Ide, Kazuko,Wakebayashi, Takao 대한핵의학회 1971 핵의학 분자영상 Vol.5 No.1
"In 1925 Rosenthal and White introduced a bromosulfophthalein (BSP) dye retention test as a sensitive indicator of liver function. Even now it is regared as one of the most sensitive agents for the detection of non-icteric liver disease (liver cirrhosis, early stage of acute-hepatitis and hepatic tumor). BSP accumulates in the liver cells, conjugates with glutathione and is excreted into the bile. Therefore, a disorder in its excretion is due to a disturbance of one of these processes. Since bilirubin and BSP compete for uptake by the liver and increased serum bilirubin interferes with the colorimetric determination of BSP, it has been considered that BSP test is inappropriate for the differential diagnosis of jaundice conditions. It has been generally said that when jaundice is present, the BSP test is useless and should not be performed. In 1955, Taplin et al. labeled rose bengal, a dye similarly metabolized in the liver as BSP, with 131I and measured the hepatic excretion of this dye by external monitoring. Laster, Blahd et al. applied this method to the determination of the peripheral pool, succeeding in the diagnosis of chronic and subacute hepatic diseases without colorimetry. In 1968, Yamada, Taplin et al. suggested the possibility of differentiating so-called medical jaundice from surgical jaundice by scanning the subjects during 24 to 48 hours following intravenous injection of 131I-labeled rose bengal. As mentioned before, many authorities hold the opinion that BSP is not proper for the differential diagnosis of jaundice states. Some have tried to diagnose biliary tract obstruction by a malignant tumor by measuring BSP excretion into duodenal fluid and others by quantitating changes in serum levels of conjugated and free BSP. Furthermore, Burton et al. reported that in patients with extrahepatic obstructive jaundice, BSP retention was observed for 24 days after its administration. From a consideration of all these finding we came to a conclusion that the differential diagnosis of various jaundice states, (medical, surgical and constitutional) is possible by sequential scanning with radioisotope-labeled BSP, as with rose bengal, in accordance with procedures described by Yamada, Taplin et al. The evidence suggested that labeled BSP might make a more important contribution than rose bengal. "
Adsorption and Reaction of CO and NO on Ir(111) Under Near Ambient Pressure Conditions
Ueda, K.,Suzuki, K.,Toyoshima, R.,Monya, Y.,Yoshida, M.,Isegawa, K.,Amemiya, K.,Mase, K.,Mun, B. S.,Arman, M. A. Springer Science + Business Media 2016 Topics in catalysis Vol.59 No.5
<P>The adsorption and reaction of CO and NO on Ir(111) have been studied by near-ambient pressure X-ray photoelectron spectroscopy (NAP-XPS) together with low-energy electron diffraction, scanning tunneling microscopy, and mass spectroscopy (MS). Under both ultrahigh vacuum (UHV) and NAP conditions CO molecules occupy on-top sites of the Ir(111) surface at room temperature (RT) by forming two-dimensional clusters. Exposure to NO under UHV conditions at RT induces partially dissociative adsorption, while NAP NO exposure leads to a Ir(111) surface that is covered by molecular NO. We conducted in-operando NAP-XPS/MS observation of the NO + (CO)-C-13 reaction under a NAP condition as a function of temperature. Below 210 degrees C adsorption of NO is inhibited by CO, while above 210 degrees C the CO inhibition is released due to partial desorption of CO and dissociative adsorption of NO starts to occur leading to associative formation of N-2. Under the most active condition studied here the Ir surface is covered by a dense co-adsorption layer consisting of on-top CO, atomic N and O, which suggests that this reaction is not a NO-dissociation-limited process but a N-2/CO2 formation-limited process.</P>
Final report on APMP.M.F-K4.b key comparison for 2 MN force
Ueda, Kazunaga,Bartel, Thomas W,Liok, Goh Hok,Hsin-Tse, Lee,Man, John,Park, Yon-Kyu,Wong, Seung-yin Springer-Verlag 2012 METROLOGIA -BERLIN- Vol.49 No.-
<P>This report gives the results of the APMP.M.F-K4.b key comparison in 2 MN force range. This regional key comparison was conducted under the Asia Pacific Metrology Program (APMP) to establish a link to the global CCM.F-K4.b key comparison.</P><P>Seven institutes participated in this key comparison. The National Metrology Institute of Japan (NMIJ/AIST) served as the pilot institute. The Korea Research Institute of Standards and Science (KRISS) and the National Institute of Standards and Technology (NIST) together with NMIJ/AIST provided links to the CCM.F-K4.b key comparison. A pair of force transducers having 2 MN nominal capacities was circulated among the participants in a star formation.</P><P>This regional key comparison revealed that all measurement results of the seven participants are coherent with the CCM.F-K4.b key comparison reference value within their uncertainties and that these participants are equivalent to each other.</P><P>Main text.To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.</P><P>The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).</P>
Ueda, Mitsutoshi,Maruyama, Toshio The Korean Ceramic Society 2012 한국세라믹학회지 Vol.49 No.1
Mass transport near grain boundary in a magnetite bi-crystal has been estimated at 823 K by finite element method. Mass transport near grain boundary strongly depends on the diffusivities along grain boundary. If grain boundary diffusion has the same oxygen activity dependence as lattice diffusion, there is no mass transport between grains and grain boundary. On the other hand, mass transport between grains and grain boundary is observed in the case that grain boundary diffusion has different oxygen activity dependence.