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- 저자 : Toshio Hori (검색결과 4 건)
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Toshio Nakamura,Haruo Yamamura,박경호,Caroline Pereira,Yoshikazu Uchida,Noriko Horie,김무조,Satoshi Itami 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.7
Alopecia is divided into two categories: androgenic alopecia and nonandrogenic alopecia. An androgen-dependent abnormality of biological functions causes alopecia in males, but the role of androgens is not yet elucidated in female pattern hair loss (FPHL). Modulation of androgenic activity is not effective in certain kinds of androgenic alopecia in females, as well as in cases of nonandrogenic alopecia in males and females. The hair growth drug, minoxidil, stimulates vascular endothelial growth factor (VEGF) production as well as vascularization and hair growth in females. Yet, because minoxidil has side effects with long-term use, a safe alternative hair growth agent is needed. Whereas hair develops after birth in mammalian species, hair mostly grows in a precocial bird, in the chicken, between hatching days 14 and 15. Therefore, we hypothesized that the chicken egg contains a key hair growth factor. In this study, we demonstrated that water-soluble peptides derived from the egg yolk stimulate VEGF production and human hair follicle dermal papilla cell growth. We also found that these peptides enhance murine hair growth and improve hair growth in FPHL. Finally, we characterized that water-soluble egg yolk peptides induce VEGF expression through insulin growth factor-1 receptor activation-induced hypoxia-inducible factor-1α transcription pathway. We have given the name “hair growth peptide (HGP)” to this water-soluble egg yolk peptide.
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Scanning Stereoscopic PIV for 3D Vorticity Measurement
Jun SAKAKIBARA,Toshio HORI 한국가시화정보학회 2004 KOREA-JAPAN Joint Seminar on Particle Image Veloci Vol.- No.-
A scanning stereo-PIV system was developed to measure the three-dimensional distribution of three-component velocity in a turbulent round jet. A laser light beam produced by a high repetition rate YLF pulse laser was expanded vertically by a cylindrical lens to form a laser light sheet. The light sheet is scanned in a direction normal to the sheet by a flat mirror mounted on an optical scanner, which is controlled by a programmable scanner controller. Two high-speed mega-pixel resolution C-MOS cameras captured the particle images illuminated by the light sheet, and stereoscopic PIV method was adopted to acquire the 3D-3C-velocity distribution of turbulent round jet in an octagonal tank filled with water. The jet Reynolds number was set at Re = 1000 and the streamwise location of the measurement was fixed at approximately x = 40D. Time evolution of three-dimensional vortical structure, which is identified by vorticity, is visualized. It revealed that the existence of a group of hairpin-like vortex structures was quite evident around the rim of the shear layer of the jet. Turbulence statistics shows good agreement with the previous data, and divergence of a filtered (unfiltered) velocity vector field was 7% (22%) of root-mean-squared vorticity value.
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Masatoshi Ogawa,Hiroshi Endo,Hiroyuki Fukuda,Hiroyoshi Kodama,Toshio Sugimoto,Takeshi Horie,Tsugito Maruyama,Masao Kondo 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
A cooling control method based on a model predictive control (MPC) for a modular datacenter utilizing the fresh-air is proposed. The proposed method reduces the total energy consumption of information technology (IT) equipment and cooling facilities in the data center, while considering a relationship between energy-savings and the temperature information of IT equipment. This method based on MPC controls the central processing unit (CPU) temperature in servers by facility fans for cooling. To design the proposed method, it is developed a prediction model that represents the CPU temperature by the revolution speed of facility fans, the fresh-air temperature, utilization of servers, and other factors. Furthermore, the proposed control method is applied to the actual modular data center. The energy consumption of the proposed method is compared with that of a traditional method, which has controlled the temperature difference between the inlet and outlet of the server racks based on proportional integral (PI) control. Actual comparison experiments with traditional method are provided to validate effectiveness of the proposed method. The results show that the proposed method realizes energy-savings of more than 20% compared to the traditional control method in the actual modular datacenter.
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Model-Based Control for High-Pressure Fuel Pumps
Yoichi Iihoshi,Shin Yamauchi,Ryusei Miura,Yoshikuni Kurashima,Toshio Hori 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
This document describes a model-based controller for a high-pressure fuel system on a direct injection engine. This controller drives a high-pressure fuel pump with an inverse pump model and keeps injection pressure under control with a disturbance observer and a proportional (P) controller. The designed controller is a two-degrees-of-freedom control that can improve step response time and nominal pulsation at the same time. Theeffectiveness of the proposed method is investigated using real engine experiments and produces successful results compared with a PI controller.
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